Results 21 to 30 of about 162,701 (253)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Fluorescence spectroscopy as a tool for determination of organic matter removal efficiency at water treatment works [PDF]

, 2010
Organic matter (OM) in drinking water treatment is a common impediment responsible for increased coagulant and disinfectant dosages, formation of carcinogenic disinfection-by products, and microbial re-growth in distribution system.
Bridgeman, John, Baker, Andy, Bieroza, Magdalena   +2 more
core   +6 more sources

Disinfection of Orthodontic Elastomers and Its Effects on Tensile Strength [PDF]

, 2022
OBJECTIVE: This study aimed to investigate the effect of different disinfection protocols on the mechanical properties of orthodontic elastomeric ligatures (EL), an important issue to biosafety improvement and infection control, and to avoid cross ...
Eduardo G Mota, Berni Osorio, Leandro, Martinelli de Lima, Eduardo, Leandro Berni Osorio, Macedo de Menezes, Luciane, Eduardo Gonçalves Mota, Eduardo Martinelli Santayana de Lima, Eduardo Martinelli de Lima, Makito Osawa Gutierrez, Luiz, Luiz Makito Osawa Gutierrez, Luciane Macedo de Menezes, Gonçalves Mota, Eduardo, Luiz Makito, null null   +13 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

ULK1 mediated autophagy in airway cells during Aspergillus infection

Frontiers in Microbiology
IntroductionAspergillus fumigatus is a major airborne fungal pathogen that causes invasive aspergillosis in immunocompromised individuals. This study aims to elucidate the autophagic mechanisms activated following the internalization of A.
Fangyan Chen, Rui Zhao, Yuqing Sun, Yuqing Sun, Yangxuan Lin, Xiao Cui, Xiao Cui, Jingya Zhao, Yingsong Hu, Zelei Wang, Dingchen Li, Mandong Hu, Mandong Hu, Li Han   +13 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Additively Manufactured Geometry‐Reconfigurable Soft Neural Probes With Monolithic Multifunctionality

Advanced Functional Materials, EarlyView.
A geometry‐reconfigured additive manufacturing strategy converts planar printed soft materials into soft compact neural probes with integrated hydrogel electrodes and microfluidic channels. The resulting NeuroMAP platform enables scalable multichannel recording, localized chemical delivery, stable in vivo electrophysiological recording, and reduced ...
Hyunjin Lee, Xinyi Wang, Sirui Li, Jihyang Park, Hyunseok Lee, Jianting Yao, Kedar Narayan, Yuqi Wang, Jiashu Ren, Yueqi Deng, Salahuddin Ahmed, Denver I. Greenawalt, Archana Pandiyan, Loganathan Veeramuthu, Chi‐Ching Kuo, Tao Zhou   +15 more
wiley   +1 more source

Assessing the risk of Staphylococcus aureus contamination and occupational exposure on high-frequency contact surfaces in funeral venues

Frontiers in Public Health
BackgroundFuneral industry workers face potential microbial exposure when handling corpses, yet quantitative risk assessments for specific pathogens like Staphylococcus aureus remain limited.ObjectiveThis study assessed health risks to funeral staff from
Pan Sun, Peiru Xu, Li Chen, Fang Chen, Bin Zhang, Lei Wu   +5 more
doaj   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Analysis and implementation of EN ISO 15883 technical standard: execution of type tests on medical devices for thermal-disinfection and development of a prototype [PDF]

, 2022
openAnalisi e applicazione della norma tecnica EN ISO 15883: esecuzione di prove interne su dispositivi medici per la termo-disinfezione e sviluppo di un progetto prototipaleAnalysis and implementation of EN ISO 15883 technical standard: execution of ...
MARIGO, ALESSANDRO
core