Results 81 to 90 of about 162,701 (253)

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

Advanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu, Fan Jia, Yixian Mu, Wanzhe Liu, Dingqi Tang, Qiao Jin, Jian Ji, Youxiang Wang   +7 more
wiley   +1 more source

The determination of polymeric derivatives of guanidine in disinfectants by two-phase titration

Тонкие химические технологии, 2015
The article considers the results of identifying the disinfectant water-soluble guanidines polymers by means of methods including spectrophotometry, infrared spectroscopy, fluorescence analysis, as well as the use of gold nanoparticles.
O. I. Kozoor, L. A. Nosikova, K. A. Shestakov, A. N. Kochetov   +3 more
doaj  

Effects of microwave irradiation on the parameters of hydrogel contact lenses [PDF]

, 2001
Ten brands of hydrogel contact lenses were selected from five of the six British Approved Name lens classification groups to test in vitro the effects of repeated heat disinfection by means of microwave irradiation.
Crabbe, A, Thompson, P
core  

Electronics‐Free Visual Monitoring of Dry Eye Disease‐Related Tear Biomarkers Using Smart Scleral Lenses

Advanced Science, EarlyView.
An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Ziheng Wang, Sang Mok Park, Dawn Meyer, Seul Ah Lee, Yumin Dai, Tianhao Yu, Taewoong Park, Feiyang Li, Jason Gerard Jedlicka, Tristan Michael Long, Oluwabunmi T. Oladele, Gillian C. Shaw, Shin Ae Park, Pete S. Kollbaum, Young L. Kim, Chi Hwan Lee   +15 more
wiley   +1 more source

Evaluation of UV-Chlorine Processes for Enhanced Disinfection in Drinking Water: case of study [PDF]

The presence of natural organic matter (NOM) is the main cause for disinfection byproducts (DBP) formation, upon final chlorination. In this context, drinking water managers must maximize NOM removal and optimize chlorine dosage.
Cabrera-Codony A., Antonelli M., Ferràndez-Galceran L., Cantoni B., Stefanoni M., Matracchi M., Monclús H.   +6 more
core  

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

Highly sensitive and specific detection of aminoglycoside resistance methylase gene armA by multiple cross displacement amplification-CRISPR/Cas12a technique

Frontiers in Cellular and Infection Microbiology
IntroductionThe 16S rRNA methylase armA serves as a key molecular determinant conferring high-level resistance to aminoglycoside antibiotics in bacterial pathogens.
Lin Gong, Lin Gong, Juan Wang, Yuandong Zhang, Huiqiong Xu, Xiaoli Liu, Xiaomin Chen, Meiling Li, Yao Li, Liqun Wu, Yimei Wang, Xiantao Shen   +11 more
doaj   +1 more source

Clinical trial of a patient-operated microwave care system for hydrogel contact lenses [PDF]

, 2001
The clinical effects of a patient-operated system of microwave disinfection for soft contact lenses were assessed in a prospective pilot trial involving 103 patients who were drawn from five optometric practices.
Crabbe, A, Thompson, P
core  

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source