Results 41 to 50 of about 597,728 (330)

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

Lunate dislocation

Journal of the Belgian Society of Radiology, 2014
A 38 year-old patient was admitted to the emergency department after road accident due to pain on palpation of the right wrist, the 1st and the 2nd finger of the right hand. The patient was subsequently referred for an X-ray. Following the proper positioning of the patient and the systematic analysis of the wrist X-ray (PA and lateral view), a lunate ...
Filippitzi, Fotini, Dallaudière, Benjamin, Omoumi, Patrick, Lecouvet, Frédéric, Lefere, Mathieu, Vande Berg, Bruno, Larbi, Ahmed   +6 more
openaire   +6 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Simultaneous enhancement of strength and ductility with nano dispersoids in nano and ultrafine grain metals: a brief review

Reviews on Advanced Materials Science, 2020
Grain refinement is the most universal and effective method of strengthening metallic materials, which is known as the “Hall-Petch” relationship. However, when grain size is refined to sub-micro regime (Ultrafine Grain, UFG) or even nano regime (Nano ...
Hu Yusheng, Yu Ziyun, Fan Genlian, Tan Zhanqiu, Zhou Jiandang, Zhang Hao, Li Zhiqiang, Zhang Di   +7 more
doaj   +1 more source

A continuum model for dislocation dynamics in three dimensions using the dislocation density potential functions and its application in understanding the micro-pillar size effect

, 2015
In this paper, we present a dislocation-density-based three-dimensional continuum model, where the dislocation substructures are represented by pairs of dislocation density potential functions (DDPFs), denoted by $\phi$ and $\psi$.
Xiang, Yang, Zhu, Yichao
core   +1 more source

Mobility of Dislocations in Aluminum [PDF]

, 1969
The velocities of individual dislocations of edge and mixed types in pure aluminum single crystals were determined as a function of applied‐resolved shear stress and temperature.
Gorman, J. A., Vreeland, T., Jr., Wood, D. S.   +2 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Minimum energy path for the nucleation of misfit dislocations in Ge/Si(001) heteroepitaxy

, 2016
A possible mechanism for the formation of a 90{\deg} misfit dislocation at the Ge/Si(001) interface through homogeneous nucleation is identified from atomic scale calculations where a minimum energy path connecting the coherent epitaxial state and a ...
Ala-Nissila, Tapio, Granato, Enzo, Jonsson, Hannes, Maras, Emile, Stukowski, Alexander, Trushin, Oleg, Ying, See Chen   +6 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Eshelbian dislocation mechanics: $J$-, $M$-, and $L$-integrals of straight dislocations

, 2017
In this work, using the framework of (three-dimensional) Eshelbian dislocation mechanics, we derive the $J$-, $M$-, and $L$-integrals of a single (edge and screw) dislocation in isotropic elasticity as a limit of the $J$-, $M$-, and $L$-integrals between
Agiasofitou, Eleni, Lazar, Markus
core   +1 more source