Results 71 to 80 of about 622,415 (331)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Dislocation constriction and cross-slip in Al and Ag: an ab initio study

, 2002
A novel model based on the Peierls framework of dislocations is developed. The new theory can deal with a dislocation spreading at more than one slip planes.
B. Joós, D.J.H. Cockayne, F.R.N. Nabarro, G. Lu, G. Lu, G. Lu, Gang Lu, J. Hartford, M.C. Payne, M.S. Duesbery, Nicholas Kioussis, S. Rao, T. Rasmussen, V.V. Bulatov, Vasily V. Bulatov, Y.M. Juan   +15 more
core   +1 more source

Relaxation times for atom dislocations in crystals [PDF]

, 2015
We study the relaxation times for a parabolic differential equation whose solution represents the atom dislocation in a crystal. The equation that we consider comprises the classical Peierls-Nabarro model as a particular case, and it allows also long ...
Patrizi, Stefania, Valdinoci, Enrico
core   +4 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

From dislocation nucleation to dislocation multiplication in ceramic nanoparticle

Materials Research Letters, 2021
Magnesium oxide nanocubes are compressed along the [001] direction in situ in the transmission electron microscope. Incipient plasticity in the smaller samples is characterized by the nucleation of few $ \raise.5ex\hbox{$\scriptstyle 1$}\kern-.1em/\kern-.
Inas Issa, Lucile Joly-Pottuz, Jonathan Amodeo, David J. Dunstan, Claude Esnouf, Julien Réthoré, Vincent Garnier, Jérôme Chevalier, Karine Masenelli-Varlot   +8 more
doaj   +1 more source

The Non-Perturbative Quantum Nature of the Dislocation-Phonon Interaction

, 2016
Despite the long history of dislocation-phonon interaction studies, there are many problems that have not been fully resolved during this development.
Chen, Gang, Ding, Zhiwei, Dresselhaus, Mildred S., Li, Mingda, Liu, Hong, Meng, Qingping, Zhou, Jiawei, Zhu, Yimei   +7 more
core   +2 more sources

Safety of surgical hip dislocation in femoral head fracture and dislocation (FHFD) and avascular necrosis risk factor analysis of FHFD: midterm results confirmed by SPECT/CT and MRI [PDF]

, 2022
Yong-Cheol Yoon, Chang‐Wug Oh, Joon‐Woo Kim, Jeong Heo, Hyung Keun Song   +4 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source