Results 91 to 100 of about 191,305 (291)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Some interface theories and Hall–Petch relationship

open access: yesRoyal Society Open Science
In polycrystalline materials, an increase in the number of interfaces strengthens the material. For example, in deformation twins, deformation experiments have shown a correlation between the deformation-twin density and flow stress.
Hiroaki Yokoyama, Hiroyuki Nagahama
doaj   +1 more source

Modelling of dislocation generation and interaction during high-speed deformation of metals

open access: yes, 2000
Recent experiments by Kiritani et al. have revealed a surprisingly high rate of vacancy production during high-speed deformation of thin foils of fcc metals. Virtually no dislocations are seen after the deformation.
Leffers, T., Schiøtz, J., Singh, B. N.
core  

Dislocation nucleation and vacancy formation during high-speed deformation of fcc metals

open access: yes, 2001
Recently, a dislocation free deformation mechanism was proposed by Kiritani et al., based on a series of experiments where thin foils of fcc metals were deformed at very high strain rates.
Leffers, T., Schiøtz, J., Singh, B. N.
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Characterizing the Substructural Changes in Metals by Microindentation and Various Numerical Approaches

open access: yesMetals
This contribution compares various theories dealing with the assessment of dislocation density in metals subjected to different straining levels. The paper examines both substructure development and the evolution of dislocation densities in 1xxx, 5xxx ...
János György Bátorfi, Jurij J. Sidor
doaj   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

Investigation of the Dynamic Recrystallization of FeMnSiCrNi Shape Memory Alloy under Hot Compression Based on Cellular Automaton

open access: yesMetals, 2019
Dynamic recrystallization (DRX) takes place when FeMnSiCrNi shape memory alloy (SMA) is subjected to compression deformation at high temperatures. Cellular automaton (CA) simulation was used for revealing the DRX mechanism of FeMnSiCrNi SMA by predicting
Yu Wang   +3 more
doaj   +1 more source

First-principles calculation of H vibrational excitations at a dislocation core of Pd

open access: yes, 2010
Palladium is an ideal system for understanding the behavior of hydrogen in metals. In Pd, H is located both in octahedral sites and in dislocation cores, which act as nanoscale H traps and form Cottrell atmospheres.
Lawler, Hadley M., Trinkle, Dallas R.
core   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic   +6 more
wiley   +1 more source

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