Results 181 to 190 of about 5,552,271 (346)

Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative.

open access: yesArchives of General Psychiatry, 2011
K. Merikangas   +16 more
semanticscholar   +1 more source

Autism spectrum disorder

open access: yesNature Reviews Disease Primers, 2020
C. Lord   +11 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

PB2620: NIGHTTIME SYMPTOMS ARE ASSOCIATED WITH FATIGUE AMONG CHILDREN AND ADOLESCENTS WITH CHRONIC ITP: DATA FROM THE ITP NATURAL HISTORY STUDY REGISTRY

open access: yesHemaSphere, 2023
Jennifer Diraimo   +4 more
doaj   +1 more source

Suicidal Ideation in Pediatric Orthopaedic Patients. [PDF]

open access: yesJB JS Open Access
Herge WM   +7 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Associations of mental disorders in children with parents' subsequent mental disorders: nationwide cohort study from Finland and Denmark. [PDF]

open access: yesBr J Psychiatry
Hakulinen C   +8 more
europepmc   +1 more source

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