Results 281 to 290 of about 5,886,495 (367)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Neuroinflammation and white matter microstructure as mediators of cognitive deficits in offspring of parents with bipolar disorder. [PDF]

Brain Commun
Li X, Zou W, Shao R, Lu W, Chao L, Zhao X, Su KP, Lin K.   +7 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Dissecting the polygenic architecture of psychopathology via singular value decomposition of eight psychiatric genome-wide association studies and evaluation of component-based polygenic scores. [PDF]

Gen Psychiatr
Facal F, Pérez-Gutiérrez AM, Costas J.
europepmc   +1 more source

Naltrexone for Acute Management of Compulsive Sexual and Obsessive Symptoms in a Patient With a Neurodevelopmental Disorder. [PDF]

Case Rep Psychiatry
Constantin E, Deol MS, Yaun J, Singh H, Glass OM.   +4 more
europepmc   +1 more source

A comparison between dissociative subtypes of PTSD and CPTSD among trauma-exposed adolescents. [PDF]

Eur J Psychotraumatol
Bi Y, Cao C, Chen W, Liu Y, Liu P, Luo S, Zhang B, Qin H, Tang Y, Pan Y, Wang L.   +10 more
europepmc   +1 more source

Employment and industries that low-income U.S. veterans with mental illness participate in. [PDF]

Psychiatr Rehabil J
Tsai J, Ndabezitha SS, Lai H, Maroufy V.
europepmc   +1 more source

Factors Influencing Contraceptive Use Among Women With Serious Mental Illness Residing in Pennsylvania. [PDF]

Perspect Sex Reprod Health
Nikolajski C, Williams K, Hawk M, Burke JG.   +3 more
europepmc   +1 more source

Eating disorder-related electrolyte abnormalities and adverse outcomes: A systematic review and meta-analysis. [PDF]

PLoS One
Fremont D, Buh A, Hoar-Stephens C, Biyani N, Kiska R, Fung SG, Mahbub S, Zameer M, Fabiano N, Solmi M, Gibb M, Kang R, Salman M, Lee K, Milone B, Syed S, Dhaliwal S, Akbari A, Brown PA, Sood MM, Hundemer GL.   +20 more
europepmc   +1 more source