Results 51 to 60 of about 166,123,844 (288)

Chronic disorders of consciousness

Experimental and Therapeutic Medicine, 2017
Over the last 20 years, studies have provided greater insight into disorders of consciousness (DOC), also known as altered state of consciousness. Increased brain residual functions have been identified in patients with DOC due to the successful application of novel next-generation imaging technologies. Many unconscious patients have now been confirmed
Qiuyou, Xie, Xiaoxiao, Ni, Ronghao, Yu, Yuanqing, Li, Ruiwang, Huang   +4 more
openaire   +3 more sources

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

EEG complexity correlates with residual consciousness level of disorders of consciousness

BMC Neurology, 2023
Background and objective Electroencephalography (EEG) and neuroimaging measurements have been highly encouraged to be applied in clinics of disorders of consciousness (DOC) to improve consciousness detection.
Yangfeng Liu, Wentao Zeng, Na Pan, Xiaoyu Xia, Yonghua Huang, Jianghong He   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Apomorphine therapy for patients with disorders of consciousness: a multimodal open-label study

, 2021
peer reviewedIntroduction: Apomorphine, a repurposed dopaminergic drug, is a promising therapy to improve the recovery of patients with disorders of consciousness (DOC), with a postulated action on the mesocircuit.
Farber, Neal, Sala, Arianna, Thibaut, Aurore, Laureys, Steven, Gosseries, Olivia, Sanz, Leandro, Bonin, Estelle, Lejeune, Nicolas, Panda, Rajanikant, Dikenstein, David   +9 more
core  

From detection to decision: a conceptual framework of uncertainty migration in disorders of consciousness

Frontiers in Neurology
Accurate assessment of consciousness in patients with disorders of consciousness (DoC) remains a longstanding challenge in neurocritical care and neurorehabilitation.
Fangting Wang, Fangting Wang, Fangting Wang, Yufei Xue, Yufei Xue, Yufei Xue, Haibo Di, Haibo Di, Haibo Di   +8 more
doaj   +1 more source

BCI Performance and Brain Metabolism Profile in Severely Brain-Injured Patients Without Response to Command at Bedside

Frontiers in Neuroscience, 2018
Detection and interpretation of signs of “covert command following” in patients with disorders of consciousness (DOC) remains a challenge for clinicians.
Jitka Annen, Séverine Blandiaux, Nicolas Lejeune, Nicolas Lejeune, Nicolas Lejeune, Mohamed A. Bahri, Aurore Thibaut, Woosang Cho, Christoph Guger, Christoph Guger, Camille Chatelle, Camille Chatelle, Steven Laureys   +12 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Detection of residual consciousness using EEG indicators related to rectal perception: protocol for a diagnostic accuracy study

Frontiers in Neurology
IntroductionAccurate diagnosis of disorders of consciousness (DoC), including unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS), remains a long-standing and unresolved challenge in clinical practice.
Yilin Zhao, Yilin Zhao, Yitong Lian, Yitong Lian, Yinliang Qi, Steven Laureys, Steven Laureys, Steven Laureys, Steven Laureys, Haibo Di, Haibo Di, Weiqiao Zhao, Weiqiao Zhao   +12 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source