Results 81 to 90 of about 169,190,458 (279)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

2020 Partnership Report: Partnerships in a Time of Transformation

open access: yes, 2021
In 2020, the Inter-American Development Bank kicked off the new decade faced with a novel, unprecedented challenge: the COVID-19 pandemic. Fortunately, as the IDB Group sought to help the region\u27s governments and companies navigate the social ...
Inter-American Development Bank
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Gender Identity and Preferences in Children with Variations in Sex Development

open access: yesJCRPE
Objective: To assess gender-typed preferences and gender identity in children with and without variations in sex developments (VSDs). Methods: In this cross-sectional study, 78 children with VSDs (ages 3-12; mean age=7 years; 55% White, non-Hispanic ...
Canice E. Crerand   +16 more
doaj   +1 more source

Transverse testicular ectopia with disorders of sex development

open access: yesIndian Journal of Urology, 2012
Transverse testicular ectopia (TTE) is a rare congenital anomaly. Although TTE often coexists with abnormalities such as inguinal hernia and persistent Mullerian duct syndrome, disorders of sex development (DSD) in combination with TTE is extremely rare.
Katsuya Aoki   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

IDB Group Selected Development Contributions 2016-2019

open access: yes, 2020
This infographic shows selected IDB Group\u27s contributions to the Sustainable Development Goals (SDGs) reported through the Group\u27s Corporate Results Framework between 2016 and ...
Inter-American Development Bank
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Internet sex addiction: a review of empirical research [PDF]

open access: yes, 2012
The advent of the internet has added another medium in which people can engage in sexual behaviour. This ranges from the passive consumption of online pornography to the interactive exchange of sexual content in cybersex chat rooms.
Griffiths, MD
core  

Long-term Outcomes of Gender Decisions in Differences of Sex Development (DSD) from an Indian Perspective: A Multicenter Study

open access: yesJournal of Indian Association of Pediatric Surgeons
Background: Gender assignment is a central and often urgent decision in the management of differences of sex development (DSD). With growing emphasis on patient-centered care, there is an increasing need to evaluate how early gender assignment and ...
Shilpa Sharma   +8 more
doaj   +1 more source

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