Results 51 to 60 of about 25,630 (289)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

The effect of pump depletion on reversible photodegradation

, 2013
We model the effect of pump depletion on reversible photodegradation using the extended domain model[Anderson and Kuzyk, arXiv:1309.5176v1, 2013] and the Beer-Lambert law.
Anderson, Benjamin, Hung, Sheng-Ting, Kuzyk, Mark G.   +2 more
core   +1 more source

Synthesis and Photocatalytic Performance of TiO2-CNT and Magnetized Fe3O4-TiO2-CNT Multifunctional Hybrids: A Pickering Emulsion Platform for Organic Degradation [PDF]

, 2018
The oil and textile industries produce billions of gallons of wastewater containing toxic, and sometimes carcinogenic or mutagenic, chemicals that often disperse throughout wastewater as suspended oil droplets.
Mason, Erica
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Process monitoring and visualization solutions for hot-melt extrusion : a review [PDF]

, 2013
Objectives: Hot-melt extrusion (HME) is applied as a continuous pharmaceutical manufacturing process for the production of a variety of dosage forms and formulations.
De Beer, Thomas, Remon, Jean Paul, Saerens, Lien, Vervaet, Chris   +3 more
core   +2 more sources

An effective experimental and numerical approach to dye UHMWPE fibers by synergetic disperse dyestuffs blends

Journal of Engineered Fibers and Fabrics
High-performance fibers, particularly UHMWPE (Ultra-High Molecular Weight Polyethylene), are widely used in the textile industry due to their remarkable mechanical and chemical properties.
Oumaima Amara, Debbabi Faten, Nizar Meksi, Hatem Dhaouadi   +3 more
doaj   +1 more source

Synthesis of Some Novel 2-Amino-5-arylazothiazole Disperse Dyes for Dyeing Polyester Fabrics and Their Antimicrobial Activity

Molecules, 2016
The present work describes the synthesis of a series of four novel biologically active 2-amino-5-arylazothiazole disperse dyes containing the sulfa drug nucleus.
Hatem E. Gaffer, Moustafa M. G. Fouda, Mohamed E. Khalifa   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Color Characterization of Dispersed Dyes Based on Quantum Chemistry Calculations

Journal of Chemistry
The UV–visible absorption spectra of disperse dyes are intrinsically dependent on their chemical structure, a critical determinant of the dyes’ color performance.
Xuekun Xue, Yue Liu
doaj   +1 more source