Results 1 to 10 of about 321,704 (306)

Exhaustion, Non-exhaustion and Implied Licence [PDF]

IIC - International Review of Intellectual Property and Competition Law, 2018
This article explores how exhaustion and non-exhaustion of certain rights can be more coherently explained using the common law doctrine of implied licence. Exhaustion, as the name suggests, only focuses on the effect of the first sale or other transfer of ownership of the original or the copy of the work on the copyright owner, namely the consumption ...
Mysoor, Poorna
openaire   +3 more sources

Analysis of single‐cell RNAseq identifies transitional states of T cells associated with hepatocellular carcinoma

Clinical and Translational Medicine, 2020
Background Exhausted T cells and regulatory T cells (Tregs) comprise diverse subsets of tumor immunosuppressive microenvironment that play key roles in tumor progress. Understanding subset diversity in T cells is a critical question for developing cancer
Yanying Yang, Fangming Liu, Weiren Liu, Mingyue Ma, Jie Gao, Yan Lu, Li‐Hao Huang, Xiaoying Li, Yinghong Shi, Xiangdong Wang, Duojiao Wu   +10 more
doaj   +1 more source

A CD4+ T cell reference map delineates subtype-specific adaptation during acute and chronic viral infections

eLife, 2022
CD4+ T cells are critical orchestrators of immune responses against a large variety of pathogens, including viruses. While multiple CD4+ T cell subtypes and their key transcriptional regulators have been identified, there is a lack of consistent ...
Massimo Andreatta, Ariel Tjitropranoto, Zachary Sherman, Michael C Kelly, Thomas Ciucci, Santiago J Carmona   +5 more
doaj   +1 more source

Toward a New Model of Understanding, Preventing, and Treating Adolescent Depression Focusing on Exhaustion and Stress

Frontiers in Psychiatry, 2020
ObjectiveAdolescent depression is a heterogeneous disorder, with a wide variety of symptoms and inconsistent treatment response, and is not completely understood.
Toon van der Gronde, Leontien Los, Arnoud Herremans, Ronald Oosting, Rafaela Zorzanelli, Toine Pieters   +5 more
doaj   +1 more source

HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control

Frontiers in Immunology, 2022
Lymphoid tissues are an important HIV reservoir site that persists in the face of antiretroviral therapy and natural immunity. Targeting these reservoirs by harnessing the antiviral activity of local tissue-resident memory (TRM) CD8+ T-cells is of great ...
Rabiah Fardoos, Rabiah Fardoos, Sarah K. Nyquist, Sarah K. Nyquist, Osaretin E. Asowata, Samuel W. Kazer, Alveera Singh, Abigail Ngoepe, Jennifer Giandhari, Ntombifuthi Mthabela, Dirhona Ramjit, Samita Singh, Farina Karim, Søren Buus, Frank Anderson, J. Zachary Porterfield, J. Zachary Porterfield, J. Zachary Porterfield, J. Zachary Porterfield, Andile L. Sibiya, Rishan Bipath, Kumeshan Moodley, Warren Kuhn, Warren Kuhn, Bonnie Berger, Son Nguyen, Tulio de Oliveira, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Philip Goulder, Philip Goulder, Philip Goulder, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alasdair Leslie, Alasdair Leslie, Henrik N. Kløverpris, Henrik N. Kløverpris, Henrik N. Kløverpris   +40 more
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The Complex Interplay Between Emotion Regulation and Work Rumination on Exhaustion

Frontiers in Psychology, 2019
This study examined the interplay between emotion regulation strategies (reappraisal and suppression) and work-related rumination (affective work rumination and detachment from work) on exhaustion.
Martin Geisler, Sandra Buratti, Carl Martin Allwood   +2 more
doaj   +1 more source

B7-H7 Is Inducible on T Cells to Regulate Their Immune Response and Serves as a Marker for Exhaustion

Frontiers in Immunology, 2021
The discovery of immune checkpoints highlights the complexity of T cell signalling during an immune response. Upon activation, T cells express several molecules to regulate their function and to prevent overactivation.
Khang Luu, Khang Luu, Khang Luu, Khang Luu, Khang Luu, Herbert Schwarz, Herbert Schwarz, Herbert Schwarz, Herbert Schwarz, Andreas Lundqvist   +9 more
doaj   +1 more source

Life role salience and subjective well-being among Macedonian employees: Does family-supportive organization perception moderate this relationship

International Journal of Occupational Medicine and Environmental Health, 2018
Objectives As many studies have shown, one of the most important tendencies of employees nowadays is to achieve work– life balance. Organizations should develop various activities and create supportive climate, within the framework of which employees ...
Biljana Blaževska Stoilkovska, Orhideja Šurbanovska, Ana Fritzhand, Tatjana Stojanoska Ivanova   +3 more
doaj   +1 more source

Influence of Diets Enriched with Flavonoids (Cocoa and Hesperidin) on the Systemic Immunity of Intensively Trained and Exhausted Rats

Biomolecules, 2022
The aim of this study was to establish the influence of flavonoid-enriched diets on the immune alterations induced by an intensive training and a final exhaustion test in rats.
Patricia Ruiz-Iglesias, Malén Massot-Cladera, Francisco J. Pérez-Cano, Margarida Castell   +3 more
doaj   +1 more source

Exhausting the Differential [PDF]

Journal of General Internal Medicine, 2014
In this series, a clinician extemporaneously discusses the diagnostic approach (regular text) to sequentially presented clinical information (bold). Additional commentary on the diagnostic reasoning process (italic) is interspersed throughout the discussion.
Joseph, Chiovaro, Vanja, Douglas, Anuj, Gaggar, Gurpreet, Dhaliwal   +3 more
openaire   +2 more sources