Results 51 to 60 of about 25,770 (283)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Surface modification of polyester using chicken feather keratin hydrolysate to improve water absorbency and dye uptake [PDF]

, 2019
PET fiber has an intrinsic low hydrophilic character and an inactive surface which make it uncomfortable for wearing purpose. Moreover, it is difficult to colour polyester fabric other than disperse dyes.
Bayrau Nigusse, Abreha Bayrau, Fante, Kinde A., Mengistie, D. A., Tseghai, Granch Berhe, Van Langenhove, Lieva   +4 more
core   +1 more source

LACTOSE TO NATURALIZE TEXTILE DYES [PDF]

, 2007
Many natural dyes, for example carminic acid, are soluble in water. We present a simple strategy to naturalize synthetic azadyes through their linkage with lactose to induce their water solubility.
Elena Frino, Giorgio Catelani, Jalal Isaad, Massimo Rolla, Roberto Bianchini   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Centrifugal melt spinning of polyvinylpyrrolidone (PVP)/triacontene copolymer fibres [PDF]

, 2016
Polyvinylpyrrolidone/1-triacontene (PVP/TA) copolymer fibre webs produced by centrifugal melt spinning were studied to determine the influence of jet rotation speed on morphology and internal structure as well as their potential utility as adsorbent ...
A Dąbrowski, A Groszek, A Peterlin, AJ Schouten, AN Derbyshire, C Moreno-Castilla, CH Giles, Christopher M. Carr, CJ Ellison, D Blundell, D Neugebauer, DG Yu, F Franks, G Puccetti, H Chen, J Israelachvili, JT McCann, JW Hearle, JW Hearle, K Gramley, K Sarkar, K Sui, L Zheng, M Brugnara, Machmudah S Wahyudiono, MS El-Geundi, MT Razzak, N Ueno, P Barham, P Smith, PA Carneiro, PB Rai, R Camini, R Christie, R Pashley, RB Login, S Allen, S Bandla, S Sethia, SL Liu, Stephen. J. Russell, T Arndt, T O’Haire, Tom O’Haire, WJ Brittain, Z McEachin   +45 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

An effective experimental and numerical approach to dye UHMWPE fibers by synergetic disperse dyestuffs blends

Journal of Engineered Fibers and Fabrics
High-performance fibers, particularly UHMWPE (Ultra-High Molecular Weight Polyethylene), are widely used in the textile industry due to their remarkable mechanical and chemical properties.
Oumaima Amara, Debbabi Faten, Nizar Meksi, Hatem Dhaouadi   +3 more
doaj   +1 more source

Synthesis of Some Novel 2-Amino-5-arylazothiazole Disperse Dyes for Dyeing Polyester Fabrics and Their Antimicrobial Activity

Molecules, 2016
The present work describes the synthesis of a series of four novel biologically active 2-amino-5-arylazothiazole disperse dyes containing the sulfa drug nucleus.
Hatem E. Gaffer, Moustafa M. G. Fouda, Mohamed E. Khalifa   +2 more
doaj   +1 more source

Testing the diffusion hypothesis as a mechanism of self-healing in Disperse orange 11 doped in PMMA

, 2011
In this work, we show that reversible photodegradation of Disperse Orange 11 doped in PMMA is not due to dye diffusion - a common phenomenon observed in many dye-doped polymers.
Agari, Anderson, Dubois, Embaye, Enge, Galvan-Gonzalez, Howell, Howell, Kim, Lee, Lefin, Li, Mark G. Kuzyk, Nathan Dawson, Sekkat, Shiva K. Ramini, Yager   +16 more
core   +1 more source