Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Immigration and demographic change in the metropolitan area of Madrid
Anales de Geografía de la Universidad Complutense, 2009 The paper analyzes the evolution of the population and its dynamic components in the metropolitan area of Madrid between 1996 and 2006. Work has been done with data from the Municipal Population Census and the Movement of Natural Population.
Enrique Pozo Rivera +1 more
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Software Radio para antenas inteligentes en comunicaciones personales multistandard [PDF]
, 1998 Peer ReviewedPostprint (published ...
Cabrera-Bean, Margarita +6 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Preparación y caracterización de compuestos poliméricos a base de aceite de linaza epoxidado y nanotubos de carbono [PDF]
, 2013 Establecer las condiciones de preparación de compuestos poliméricos a base de aceite de linaza y nanotubos de carbono no modificados y modificados químicamente, y llevar a cabo su caracterización por FT-IR, SEM, propiedades eléctricasSe alcanzó el ...
CAMACHO LOPEZ, MARCO ANTONIO +5 more
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An account on the taxonomy and molecular diversity of a marine rock-pool dweller, Tigriopus fulvus (Copepoda, Harpacticoida) [PDF]
, 2019 The copepod genus Tigriopus Norman, 1869 is distributed worldwide in coastal rock pools and it is currently considered to include 14 valid species.
Eduardo Belda +4 more
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Interpretación de la dispersión de datos en contexto de riesgo por profesoras en formación [PDF]
, 2015 Esta investigación tiene como objetivo explorar el razonamiento de profesoras en formación, acerca de la dispersión de los datos (variabilidad o variación) cuando la analizan en problemas que involucran riesgo.
Altamirano, José Antonio +2 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Revista Centro Azúcar, 2022 Introducción: Las emisiones de gases contaminantes a la atmósfera de los sistemas de generación de vapor están determinadas por el tipo y la composición del combustible.
Arianna Alvarez Cruz +3 more
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