Results 91 to 100 of about 1,229,509 (297)

Nano-Management of Linear Properties of Photonic Crystal Fibers

Communications, 2014
The array of nanometer air holes positioned in the core can significantly modify the properties of guided mode in photonic crystal fiber. Changing geometrical properties of nanometer holes enables tuning of fiber dispersion and the effective mode area ...
Daniel Kacik, Peter Tatar, David Liachovicky   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Diagnosing hemodynamically important coronary atherosclerosis in stable angina patients: the role of stress test dynamics of QT duration and dispersion

Кардиоваскулярная терапия и профилактика, 2008
Aim. To study a potential link between increased QT dispersion (dQT) during physical stress test (PST) and coronary artery (CA) atherosclerosis in patients with coronary heart disease (CHD).Material and methods. In total, 116 CHD patients with Functional
N. V. Furman, P. Ya. Dovgalevsky, S. S. Shmatova   +2 more
doaj  

Research of dispersion characteristics of optical glass

Компьютерная оптика
Dispersion characteristics of optical glass are considered. An approach to research of dispersion characteristics of optical glass is proposed, requiring the measurement of the refractive index at only three wavelengths, which simplifies the measurement ...
A.I. Yurin, G.N. Vishnyakov, V.L. Minaev
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

DETERMINATION OF GRANULOMETRIC COMPOSITION OF PULVERIZED COAL BY AUTOMATED SYSTEM

Приборы и методы измерений, 2015
The method of granulometric composition determination of dry powders by a shadow method in the automated system of determination of quantitative structure is described. The granulometric analysis of coal-dust fuel particles is carried out.
A. S. Chernenko, S. M. Kontush, A. S. Zinchenko, V. V. Kalinchak, V. V. Kalugin   +4 more
doaj  

Dispersion stability of thermal nanofluids

, 2017
Thermal nanofluids, the engineered fluids with dispersed functional nanoparticles, have exhibited extraordinary thermophysical properties and added functionalities, and thus have enabled a broad range of important applications.
F. Yu, Yingying Chen, Xingbo Liang, Jiale Xu, Chiahsun Lee, Q. Liang, P. Tao, T. Deng   +7 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source