Results 111 to 120 of about 2,741,856 (378)

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

NEW DEPARTMENTAL RECORDS OF DIGITONTHOPHAGUS GAZELLA (COLEOPTERA: SCARABAEIDAE) IN COLOMBIA

open access: yesActa Biológica Colombiana, 2012
The introduced dung beetle Digitonthophagus gazella was reported for the Caribbean Region of Colombia in the 90’s. During a survey carried out along the Magdalena River new records of the presence of this species were found in the departments of Boyacá ...
Jorge Ari Noriega   +3 more
doaj  

Lorentz symmetry from a random Hamiltonian

open access: yes, 2015
We match the density of energy eigenstates of a local field theory with that of a random Hamiltonian order by order in a Taylor expansion. In our previous work we assumed Lorentz symmetry of the field theory, which entered through the dispersion relation.
Albrecht, Andreas, Iglesias, Alberto
core   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

The Best of All Worlds: Streptococcus pneumoniae Conjunctivitis through the Lens of Community Ecology and Microbial Biogeography

open access: yesMicroorganisms, 2019
The study of the forces which govern the geographical distributions of life is known as biogeography, a subject which has fascinated zoologists, botanists and ecologists for centuries.
Lawson Ung   +5 more
doaj   +1 more source

Three-dimensional dispersion induced by extreme tensile strain in La_(2–x)Sr_xCuO_4 films [PDF]

open access: yes, 2006
The electronic band structure probed by angle-resolved photoemission spectroscopy on thin epitaxial La2–xSrxCuO4 films under extreme tensile strain shows anomalous features compatible with c-axis dispersion.
Abrecht, M.   +5 more
core  

Long continuously chirped fibre Bragg gratings for compensation of linear- and 3rd order-dispersion

open access: yes, 1997
For the first time long broadband chirped fibre Bragg gratings with a dispersion profile designed to compensate 3rd order-dispersion are presented. These results demonstrate how the increased demands for dispersion compensation at very high bit-rates can
Cole, M.J.   +4 more
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

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