Results 141 to 150 of about 2,679,470 (331)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
THE BETWEEN-PLACE AND THE CULTURAL STUDIES
Travessias, 2007 In this paper, we investigate the importance of the term in-between, theoretically constituted in Silviano Santiagos work and thoroughly used in the discursive field of the Cultural Studies.
Marcos Aurélio dos Santos Souza
doaj
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Pulp Screen Plugging Characteristics
BioResourcesAperture plugging is a phenomenon that limits both the capacity and efficiency of pulp screens, which are critical components of the papermaking process. An understanding of how plugs are created and how they can be avoided can enhance the manufacture of
Parsa Aryanpour +2 more
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Doppler and Non-Doppler Shifts in Dispersion Relations for Rossby Waves and Galilean Invariance
Russian Journal of Earth SciencesThe purpose of this work is to draw the reader's attention to a paradoxical fact – the existence of two different dispersion relations for linear Rossby waves: with Doppler and nonDoppler shifts.
Gnevyshev Vladimir, Belonenko Tatyana
doaj +1 more source
Study of wide band-gap crystal LiCaAlF6 by IR-reflection spectroscopy and ab initio calculations
EPJ Web of Conferences, 2017 Polarized IR-reflection spectra and results of ab initio calculations of vibrational and electronic properties of LiCaAlF6 single crystal are presented. It is shown that the crystal band gap is direct. Experimental and theoretical parameters are obtained
Novikova N.N., Klimin S.A., Mavrin B.N.
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source