Results 101 to 110 of about 3,237,360 (342)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Dispersion curve calculation in viscoelastic tissue-mimicking materials using non-parametric, parametric, and high-resolution methods. [PDF]

Ultrasonics, 2021
Kijanka P, Urban MW.
europepmc   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Dynamical Structure Factors of the S=1/2 Bond-Alternating Spin Chain with a Next-Nearest-Neighbor Interaction in Magnetic Fields

, 2000
The dynamical structure factor of the S=1/2 bond-alternating spin chain with a next-nearest-neighbor interaction in magnetic field is investigated using the continued fraction method based on the Lanczos algorithm.
Castilla G., Chaboussant G., Chitra R., Coldea R., Fledderjohann A., Furusaki A., Gagliano E. R., Gerhardt C., Giamarchi T., Griffiths R. B., Heilmann I. U., Ishimura N., Ishimura N., Mila F., Mori S., Müller G., Oshikawa M., Poilblanc D., Press W. H., Riera J., Sakai T., Takahashi M., Tonegawa T., Totsuka K.   +23 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Quasi-perpendicular fast magnetosonic shock with wave precursor in collisionless plasma

, 2018
A one-dimensional particle-in-cell (PIC) simulation tracks a fast magnetosonic shock over time scales comparable to an inverse ion gyrofrequency. The magnetic pressure is comparable to the thermal pressure upstream.
d'Humières, E., Dieckmann, M. E., Moreno, Q., Ribeyre, X.   +3 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Unit Cell Optimization of Groove Gap Waveguide for High Bandwidth Microwave Applications

Applied Sciences
Recently, groove gap waveguides (GGWs) have shown significant potential in power handling and bandwidth enhancement compared to conventional waveguides.
Ghiayas Tahir, Arshad Hassan, Shawkat Ali, Amine Bermak   +3 more
doaj   +1 more source

Accurate Sparse Recovery of Rayleigh Wave Characteristics Using Fast Analysis of Wave Speed (FAWS) Algorithm for Soft Soil Layers

Applied Sciences, 2018
This paper presents a novel fast analysis of wave speed (FAWS) algorithm from the waveforms recorded by a random-spaced geophone array based on a compressive sensing (CS) platform.
Zhuoshi Chen, Baofeng Jiang, Jingjing Song, Wentao Wang   +3 more
doaj   +1 more source