Results 121 to 130 of about 536,565 (302)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Guided Waves In Slight, Azimuthally Anisotropic Formations [PDF]
, 1989 A method of calculating dispersion curves for guided waves in slight, azimuthally anisotropic formations is developed with perturbation theory. The fluid is assumed to be inviscid, the formation perfectly elastic and homogeneous, and the ·borehole wall
Cheng, C. H., Ellefsen, K. J.
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The problems at investigation of state of stress of thick orthotropic plate [PDF]
Applied and Computational Mechanics, 2007 The determination of state of stress of thick orthotropic plate is outlined here. The analytical formulations of dispersion curves for arbitrary direction of wave propagation in orthotropic plate, which we defined earlier, are used to obtain results. The
Hora P., Červená O.
doaj
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Neural Network-Driven Forward Modeling of Multipole Mode Wave Dispersion and Its Field Applications
Cejing jishuIn acoustic logging, multipole waves (such as dipole waves and quadrupole waves) generated by the sound source are dispersive mode waves, and their dispersion effects can lead to inaccurate wave velocity measurement.
ZHENG Kaiyin +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Determination of Plate Corrosion Dimension Using Nd:YAG Pulsed Laser-generated Wavefield and Experimental Dispersion Curves. [PDF]
Materials (Basel), 2020 Tola KD, Quoc Tran D, Yu B, Park S.
europepmc +1 more source