Results 101 to 110 of about 948,438 (322)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Achromatic telescopic squeezing scheme and application to the LHC and its luminosity upgrade
Physical Review Special Topics. Accelerators and Beams, 2013 A novel optics concept, the achromatic telescopic squeezing (ATS) scheme has been invented in the context of the Large Hadron Collider (LHC) upgrade studies, and chosen as the baseline scheme for the optics and layout of the recently approved high ...
Stéphane Fartoukh
doaj +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Breaking the angular dispersion limit in thin film optics by ultra-strong light-matter coupling [PDF]
Andreas Mischok +5 more
openalex +2 more sources
Dispersion-Cancelled and Dispersion-Sensitive Quantum Optical Coherence Tomography
Optics Express, 2004 Quantum optical coherence tomography (QOCT) makes use of an entangled twin-photon light source to carry out axial optical sectioning. We have probed the longitudinal structure of a sample comprising multiple surfaces in a dispersion-cancelled manner while simultaneously measuring the group-velocity dispersion of the interstitial media between the ...
Magued, Nasr +3 more
openaire +2 more sources
A three-lens combined field and dispersion corrector giving telecentric imagery on optics fibres [PDF]
, 1993 C. G. Wynne
openalex +1 more source
Aging and Cancer, EarlyView.This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
New approach to LHC optics commissioning for the nonlinear era
Physical Review Accelerators and Beams, 2019 In 2017, optics commissioning strategy for low-β^{*} operation of the CERN Large Hadron Collider (LHC) underwent a major revision. This was prompted by a need to extend the scope of beam-based commissioning at high energy, beyond the exclusively linear ...
E. H. Maclean +14 more
doaj +1 more source