Results 101 to 110 of about 1,099,801 (352)

High-contrast 40 Gb/s operation of a 500 um long silicon carrier-depletion slow wave modulator

, 2012
This paper was published in OPTICS LETTERS and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://dx.doi.org/10.1364/OL.37.003504.
Brimont, Antoine Christian Jacques, Fedeli, J. M., Gardes, F. Y., Martí Sendra, Javier, Reed, G. T., Sanchis Kilders, Pablo, Thomson, D. J.   +6 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Dispersion managed mode-locking dynamics in a Ti:Sapphire laser

, 2005
We present what is to our knowledge the most complete 1-D numerical analysis of the evolution and the propagation dynamics of an ultrashort laser pulse in a Ti:Sapphire laser oscillator.
Helder M. Crespo, Marco V. Tognetti, Miguel N. Miranda   +2 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Dispersive Sweatt Model for Broadband Lens Design with Metasurfaces

Photonics
The Sweatt model has been extensively used to design optical systems containing diffractive optical elements (DOEs) because it captures the dispersive characteristics of DOEs.
Weiyu Chen, Ko-Han Shih, C. Kyle Renshaw
doaj   +1 more source

Cascaded forward Brillouin scattering to all Stokes orders

New Journal of Physics, 2017
Inelastic scattering processes such as Brillouin scattering can often function in cascaded regimes and this is likely to occur in certain integrated opto-acoustic devices.
C Wolff, B Stiller, B J Eggleton, M J Steel, C G Poulton   +4 more
doaj   +1 more source

Design and analysis of a 32 × 5 Gbps passive optical network employing FSO based protection at the distribution level☆

Alexandria Engineering Journal, 2020
A cost efficient and reliable single mode fiber and free space optics based hybrid 32×5Gbps ultra dense wavelength division multiplexed-passive optical network architecture employing optical comb and polarization multiplexing is proposed.
Jawad Mirza, Waqas A. Imtiaz, Abdulah Jeza Aljohani, Ahmad Atieh, Salman Ghafoor   +4 more
doaj   +1 more source

Commissioning ShARCS: the Shane Adaptive optics infraRed Camera-Spectrograph for the Lick Observatory 3-m telescope

, 2014
We describe the design and first-light early science performance of the Shane Adaptive optics infraRed Camera-Spectrograph (ShARCS) on Lick Observatory's 3-m Shane telescope. Designed to work with the new ShaneAO adaptive optics system, ShARCS is capable
Alcott, Barry, Cowley, David, Deich, William, Dillon, Daren, Gates, Elinor, Gates, John, Gavel, Donald, Kupke, Renate, Lanclos, Kyle, McGurk, Rosalie, Norton, Andrew, Peck, Michael, Pfister, Terry, Rockosi, Constance, Sandford, Dale, Saylor, Mike, Srinath, Srikar, Ward, Jim, Weiss, Jason   +18 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Residual Dispersion in a Combiner Ring

, 2015
In this paper we present a proof to show that there exists no system of linear or nonlinear optics which can simultaneously close multiple local orbit bumps and dispersion through a single beam transport region. The second combiner ring in the CLIC drive
Apsimon, Robert, Esberg, Jakob, Owen, Hywel   +2 more
core