Results 91 to 100 of about 29,481 (310)

Superprism phenomena in planar photonic crystals [PDF]

, 2010
We utilize the anomalous dispersion of planar photonic crystals near the dielectric band edge to control the wavelength-dependent propagation of light. We typically observe an angular swing of up to 10degrees as the input wavelength is changed from 1290 ...
Wu, L, Krauss, Thomas Fraser, Karle, T, Mazilu, M   +3 more
core   +1 more source

Evidence of zero group velocity at the lowest dispersion branch through local interactions

APL Materials
Zero group velocity (ZGV) modes can be utilized in many applications in both optics and acoustics. There exist numerous realizations of metamaterials with ZGVs at higher dispersion branches.
Mahmoud M. Samak, Osama R. Bilal
doaj   +1 more source

Design and analysis of a 32 × 5 Gbps passive optical network employing FSO based protection at the distribution level☆

Alexandria Engineering Journal, 2020
A cost efficient and reliable single mode fiber and free space optics based hybrid 32×5Gbps ultra dense wavelength division multiplexed-passive optical network architecture employing optical comb and polarization multiplexing is proposed.
Jawad Mirza, Waqas A. Imtiaz, Abdulah Jeza Aljohani, Ahmad Atieh, Salman Ghafoor   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

New optical fibre based technologies and their application in highly nonlinear systems [PDF]

, 2011
This thesis investigates new fibre technologies and their application in nonlinear optical systems, designed mainly for telecommunications. The thesis includes a study of two different directions in achieving a high nonlinearity in a fibre system, namely
Camerlingo, Angela
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Roadmap on transformation optics [PDF]

, 2018
Transformation Optics asks Maxwell’s equations what kind of electromagnetic medium recreate some smooth deformation of space. The guiding principle is Einstein’s principle of covariance: that any physical theory must take the same form in any ...
John B Pendry, Horsley, SAR, Philippe Tassin, Horsley, Simon, Martini, Enrica, Smolyaninova, Vera N., Ginis, Vincent, Andrew M Weiner, Quevedo-Teruel, O, Minatti, Gabriele, Paul Kinsler, Galdi, Vincenzo, Quevedo-Teruel, Oscar, Thompson, Robert T., Smolyaninova, Vera N.,, Pendry, John, Hao, Yang, Gratus, J, Martin McCall, McCall, M, Ebrahimpouri, Mahsa, Smolyaninova, Vera, Ulf Leonhardt, Hao, Yang,, Cummer, SA, Igor I Smolyaninov, Muamer Kadic, Leonhardt, U, Kadic, Muamer, Yang Hao, Mitchell-Thomas, Rhiannon, Li, Jensen,, Lai, Y, Vincenzo Galdi, Hao, Y, McCall, Martin,, Gratus, Jonathan, Minatti, G, Rhiannon C Mitchell-Thomas, Pendry, JB, Kinsler, Paul,, Robert T Thompson, Mahsa Ebrahimpouri, Zhu, Jian, Lukens, JM, Ginis, V, Smolyaninov, II, Oscar Quevedo-Teruel, Ginis, Vincent,, Pendry, John B., Zhu, Jain, Martini, E, Maci, S, Kinsler, Paul, Smolyaninov, Igor I, Stefano Maci, Lai, Yun, Horsley, S. A. R., Li, Jensen, Mitchell-Thomas, Rhiannon C., Steven A Cummer, Tassin, Philippe,, Maci, Stefano, Cummer, Steven, Lukens, Joseph M, Martin Wegener, Lukens, Joseph, Cummer, Steven A.,, Weiner, Andrew M.,, Thompson, Robert T.,, Zhu, J, McCall, Martin, Wegener, Martin,, Cummer, Steven A., Pendry, John B.,, Gratus, Jonathan,, Enrica Martini, S A R Horsley, Lukens, Joseph M.,, Joseph M Lukens, Manatti, Gabriele, Jonathan Gratus, Tassin, Philippe, Jensen Li, Leonhardt, Ulf,, Horsely, Simon, Smolyaninova, VN, Lai, Yun,, Leonhardt, Ulf, Lukens, Joseph M., Jian Zhu, Weiner, Andrew M., Li, J, Weiner, Andrew, Yun Lai, Mitchell-Thomas, RC, Smolyaninov, Igor I.,, Vincent Ginis, Horsley, S. A. R.,, Galdi, Vincenzo,, Weiner, AM, Weiner, Andrew M, Wegener, Martin, Vera N Smolyaninova, Horsley, S. A.R., Mitchell-Thomas, Rhiannon C.,, Minatti, Gabriele,, Zhu, Jian,, Ebrahimpouri, M, Kadic, M, Smolyaninov, Igor I., Tassin, P, Thompson, RT, Gabriele Minatti, Ebrahimpouri, Mahsa,, Martini, Enrica,, Galdi, V, Quevedo-Teruel, Oscar,, Thompson, Robert, Pendy, John, Kinsler, P, Wegener, M, Smolyaninov, Igor, Maci, Stefano,, Kadic, Muamer,   +124 more
core   +1 more source

Experimental Verification of Degenerate Band Edge Dispersion in Silicon Photonic Integrated Circuits

IEEE Photonics Journal, 2016
On resonance, periodic dielectric media of finite length exhibit large and distributed internal electric field distributions. The large and distributed fields have been exploited for applications in light emission, optical switching, and nonlinear optics.
Justin R. Burr, Michael G. Wood, Ronald M. Reano   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source