Results 101 to 110 of about 782,169 (307)
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Double-sided fresnel zone plates as high performance optics in X-ray microscopy [PDF]
X-ray microscopy describes a range of analytical techniques, specialized for the characterization of organic and inorganic samples using high energy photons.
Mohácsi, István
core +1 more source
New approach to LHC optics commissioning for the nonlinear era
In 2017, optics commissioning strategy for low-β^{*} operation of the CERN Large Hadron Collider (LHC) underwent a major revision. This was prompted by a need to extend the scope of beam-based commissioning at high energy, beyond the exclusively linear ...
E. H. Maclean +14 more
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
The use of liquid crystal adaptive optics devices in astronomy [PDF]
Images obtained from large astronomical telescopes are distorted and blurred by the effects of the atmosphere. In order to compensate for this, an adaptive optics system can be incorporated downstream from the telescope focus.
Love, G.D, Love, Gordon D.
core
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
We theoretically and numerically investigate indirect mid-infrared pulse shaping via parametric transfer, specifically difference-frequency generation. We define a quantitative measure for the fidelity of parametric transfer, and investigate the effect ...
Hanna, David C. +7 more
core +1 more source
Achromatic telescopic squeezing scheme and application to the LHC and its luminosity upgrade
A novel optics concept, the achromatic telescopic squeezing (ATS) scheme has been invented in the context of the Large Hadron Collider (LHC) upgrade studies, and chosen as the baseline scheme for the optics and layout of the recently approved high ...
Stéphane Fartoukh
doaj +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Achromatic beam deflector with electrodynamic phased arrays
Since flat optics has the feature to implement a compact system, they are widely used in various applications to replace bulky refractive optics. However, they suffer from chromatic aberrations due to dispersion, limiting their effectiveness to a narrow ...
Jungkwuen An +7 more
doaj +1 more source

