Results 111 to 120 of about 1,213,794 (338)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Experimental Verification of Degenerate Band Edge Dispersion in Silicon Photonic Integrated Circuits
IEEE Photonics Journal, 2016 On resonance, periodic dielectric media of finite length exhibit large and distributed internal electric field distributions. The large and distributed fields have been exploited for applications in light emission, optical switching, and nonlinear optics.
Justin R. Burr +2 more
doaj +1 more source
On the pre-metric foundations of wave mechanics I: massless waves
, 2009 The mechanics of wave motion in a medium are founded in conservation laws for the physical quantities that the waves carry, combined with the constitutive laws of the medium, and define Lorentzian structures only in degenerate cases of the dispersion ...
Heisenberg, Landau, Obukhov
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
High-contrast 40 Gb/s operation of a 500 um long silicon carrier-depletion slow wave modulator
, 2012 This paper was published in OPTICS LETTERS and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://dx.doi.org/10.1364/OL.37.003504.
Brimont, Antoine Christian Jacques +6 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Optical microfibers and nanofibers
Nanophotonics, 2013 As a combination of fiber optics and nanotechnology, optical microfibers and nanofibers (MNFs) have been emerging as a novel platform for exploring fiber-optic technology on the micro/nanoscale.
Wu Xiaoqin, Tong Limin
doaj +1 more source
, 2015 Excitons, composite electron-hole quasiparticles, are known to play an important role in optoelectronic phenomena in many semiconducting materials.
Gartstein, Yuri N. +2 more
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source