Results 71 to 80 of about 1,213,794 (338)

Stable propagation of pulsed beams in Kerr focusing media with modulated dispersion

open access: yes, 2004
We propose the modulation of dispersion to prevent collapse of planar pulsed beams which propagate in Kerr-type self-focusing optical media. As a result, we find a new type of two-dimensional spatio-temporal solitons stabilized by dispersion management ...
Michinel, Humberto   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diffusion of optical pulses in dispersion-shifted randomly birefringent optical fibers

open access: yes, 2004
An effect of polarization-mode dispersion, nonlinearity and random variation of dispersion along an optical fiber on a pulse propagation in a randomly birefringent dispersion-shifted optical fiber with zero average dispersion is studied.
Abdullaev   +27 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Commissioning ShARCS: the Shane Adaptive optics infraRed Camera-Spectrograph for the Lick Observatory 3-m telescope

open access: yes, 2014
We describe the design and first-light early science performance of the Shane Adaptive optics infraRed Camera-Spectrograph (ShARCS) on Lick Observatory's 3-m Shane telescope. Designed to work with the new ShaneAO adaptive optics system, ShARCS is capable
Alcott, Barry   +18 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

A review of dielectric optical metasurfaces for wavefront control

open access: yesNanophotonics, 2018
During the past few years, metasurfaces have been used to demonstrate optical elements and systems with capabilities that surpass those of conventional diffractive optics.
Kamali Seyedeh Mahsa   +3 more
doaj   +1 more source

Modulation Format and Digital Signal Processing for IM-DD Optics at Post-200G Era

open access: yesJournal of Lightwave Technology
200-Gb/s per lane intensity-modulation (IM) direct-detection (DD) optics are being commercialized to support 800G and 1.6T applications inside datacenters.
D. Che, X. Chen
semanticscholar   +1 more source

Two-octave-spanning dispersion-controlled precision optics for sub-optical-cycle waveform synthesizers

open access: yes, 2014
Two-octave-spanning precision dispersive mirror systems are demonstrated, providing a new enabling technology for pulse-energy and bandwidth scaling of sub-cycle optical waveform synthesizers. We propose and characterize new dispersion management schemes
Shih-Hsuan Chia   +5 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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