Results 81 to 90 of about 58,186 (307)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Design of Endlessly Single Mode Photonic Crystal Fibers with Desirable Properties using HC-EDA Algorithm

Iranian Journal of Electrical and Electronic Engineering, 2015
In this article, Hill Climbing (HC) and Estimation of Distribution Algorithm (EDA) are integrated to produce a hybrid intelligent algorithm for design of endlessly Single Mode Photonic Crystal Fibers (SMPCFs) structure with desired properties over the C ...
M. Pourmahyabadi
doaj  

Advanced fibre Bragg gratings: application to dispersion compensation

, 1999
This thesis presents the design and fabrication issues related to advanced fibre Bragg gratings with particular emphasis on realising novel devices with application to dispersion compensation.
Durkin, Michael Kevan
core  

Model weights and parameter (slope) estimates from information-theoretic analysis of (a) species richness and (b) functional dispersion.

, 2018
Model weights and parameter (slope) estimates from information-theoretic analysis of (a) species richness and (b) functional dispersion.
Paulo Estefano D. Bobrowiec (754291), Alexander Arévalo-Sandi (4971631), Darren Norris (623285), Victor Juan Ulises Rodriguez Chuma (4971628)   +3 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Accurate Chromatic Dispersion Characterization of Photonic Integrated Circuits

IEEE Photonics Journal, 2012
An accurate technique to characterize chromatic dispersion and its slope versus wavelength is reported. The method is based on a heterodyne Mach-Zehnder interferometer, which is immune to thermal phase noise by using a counterpropagating reference beam ...
S. Mas, J. Matres, J. Marti, C. J. Oton
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Heavily Germanium-Doped Silica Fiber With a Flat Normal Dispersion Profile

IEEE Photonics Journal, 2015
A heavily germanium-doped (Ge-doped) silica fiber with a four-layer refractive index profile is proposed to obtain all normal flat dispersion property. The waveguide dispersion in the fiber can be modified by adjusting the fiber parameters, including the
C. C. Wang, M. H. Wang, J. Wu
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Impact of shear wave dispersion slope analysis for assessing the severity of myocarditis. [PDF]

Sci Rep, 2022
Amioka N, Takaya Y, Nakamura K, Kondo M, Akazawa K, Ohno Y, Ichikawa K, Nakayama R, Saito Y, Akagi S, Miyoshi T, Yoshida M, Morita H, Ito H.   +13 more
europepmc   +1 more source