Results 151 to 160 of about 1,127,739 (309)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
CIVIL CONFLICT AND FORCED MIGRATION: THE MICRO DETERMINANTES AND THE WELFARE LOSSES OF DISPLACEMENT IN COLOMBIA [PDF]
During the last decade, forced internal displacement in Colombia has been a growing phenomenon closely linked to the escalation of the internal armed conflict - particularly in rural areas.
Ana Maria Ibáñez +1 more
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The Wage and Non-wage Costs of Displacement: Evidence from Russia [PDF]
This paper is the first to analyze the costs of job loss in Russia, using unique new data from the Russian Longitudinal Monitoring Survey over the years 2003-2008, including a special supplement on displacement that was initiated by us.
H. Lehmann +3 more
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Azerbaijan : IDPs still trapped in poverty and dependence / Internal Displacement Monitoring Centre
, 2008 unknown
core +1 more source
Wages and the risk of displacement [PDF]
In this paper a simultaneous-equations model of firm closing and wage determination is specified in order to analyse how wages adjust to unfavorable product demand shocks that raise the risk of displacement through firm closing, and to what extent an ...
Carneiro, Anabela, Portugal, Pedro
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, 2020 A yearly updated map on the internal displacement of peoples around the ...
Internal Displacement Monitoring Centre
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Shape Sensing of Post-Buckling Shear Panels Using Distributed Optical Fiber Sensors and Ko's Displacement Theory: Comparison with Digital Image Correlation. [PDF]
Sensors (Basel)Aceti P, Stammel S, Sala G, Bisagni C.
europepmc +1 more source