Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Fusion of Embedded Vision and Intelligent Algorithms for Non-Contact Deformation Monitoring. [PDF]
Dong M, Liu X, Hu H, Zahra E, Wang K.
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Cross-Modal Graph Attention for Bridge SHM Data Imputation. [PDF]
Xiong J, Hu L, Meng X, An X, Xie Y.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Education for IDPs: poor marks [PDF]
Brookings Bern Project on Internal Displacement
doaj
CT-based micromotion analysis for tracking fracture displacement and fragment movement in trochanteric hip fractures: an agreement study. [PDF]
Åberg H +3 more
europepmc +1 more source
Comprehensive human genome amplification using multiple displacement amplification
F. Dean +14 more
semanticscholar +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Determining the Correlation and Effect of Rectal and Bladder Volume Change in Shift of Planning Target Volume and Calculating Planning Target Volume Margin with Van Herk Formula in Prostate Cancer Tomotherapy. [PDF]
Shabaninejad V +5 more
europepmc +1 more source

