Results 121 to 130 of about 928,593 (318)

CIVIL CONFLICT AND FORCED MIGRATION: THE MICRO DETERMINANTES AND THE WELFARE LOSSES OF DISPLACEMENT IN COLOMBIA [PDF]

open access: yes
During the last decade, forced internal displacement in Colombia has been a growing phenomenon closely linked to the escalation of the internal armed conflict - particularly in rural areas.
Ana Maria Ibáñez   +1 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The decline of job security in the 1990s: displacement, anxiety, and their effect on wage growth [PDF]

open access: yes
This article shows that job displacement rates for high-seniority workers and a consistently constructed measure of workers' fears of job loss both rose during the 1990s.
Daniel Aaronson, Daniel G. Sullivan
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Displacement Beyond Conflict Challenges for the 21st Century

open access: yes
DISPLACEMENT BEYOND CONFLICT -- Contents -- List of Tables, Boxes and Figures -- Foreword -- Acknowledgements -- List of Abbreviations -- CHAPTER ONE: Introduction -- CHAPTER TWO: Displacement: Conceptual Difficulties -- CHAPTER THREE: Counting the ...
Morrell, Gareth., McDowell, Christopher.
core  

Perspectives on Identity, Migration, and Displacement

open access: yes, 2013
Perspectives on Identity, Migration, and Displacement -- edited by Steven Tötösy de Zepetnek, I-Chun Wang, and Hsiao-Yu Sun (Kaohsiung: National Sun Yat-sen University Press, 2010.
Sun, Hsiao-Yu   +2 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Dams, displacement, policy and law in India [PDF]

open access: yes, 1999
"This paper seeks primarily to establish some benchmarks for policy and law for displacement and rehabilitation in India. It will do this by looking briefly at the actual experience of displacement due to big dams in India in 50 years, the resistance to ...
Hemadri, Ravi   +2 more
core  

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