Results 111 to 120 of about 928,593 (318)
Multi-dimensional migration challenges in North Africa [PDF]
Forced Migration Review, 2007 Facing tighter European border controls, increasing numbers of refugees and asylum seekers from sub-Saharan countries find themselves stranded in North Africa.
Johannes van der Klaauw
doaj
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A study of tympanic membrane displacement
, 1980 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Presented in this thesis is a study relating to the measurement of tympanic membrane displacement.
Marchbanks, Robert
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
CONFIRMATION AND FALSIFICATION OF EQUILIBRIUM DISPLACEMENT MODELS
One of the most important principles in any science is testing and consequently confirmation and falsification. In agricultural economics, the equilibrium displacement model is a popular modeling approach that presently is not testable and consequently ...
Davis, George C.
core
Parameters affecting inductive displacement sensors [PDF]
, 2003 An investigation of the limitations of inductive displacement sensors (IDSs) was conducted with the use of electromagnetic finite element analysis (FEA).
Wilkinson, Michael Richard
core
Positive displacement machines : Modern design innovations and tools
, 2019 Positive Displacement Machines: Modern Design Innovations and Tools explains the design and workings of a wide range of positive displacement pumps, compressors and gas expanders.
Sultan, Ibrahim, Phung, Truong
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source