Results 91 to 100 of about 1,127,739 (309)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Immigrant agricultural workers, especially unauthorized workers, face a range of severe stressors, including isolation, chronic job insecurity, and marginalization, leading to higher rates of mental health issues compared to native-born populations. This
Helen Elizabeth Lindsay +2 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Condensation and Displacement in the Poetry of Lorine Niedecker
In this essay I explore the manifestations of condensation and displacement, the two major mechanisms identified by Freud in his study on Wit and Its Relation to the Unconscious, throughout the poetry of Lorine Niedecker.
Axel Nesme
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
TECTONOPHYSICAL SIGNS OF THE FORMATION OF STRONG EARTHQUAKE FOCI IN SEISMIC ZONES OF CENTRAL ASIA
Vibrations of the Earth crust and variations in the physical fields of the Earth atmosphere and ionosphere are continuously monitored by a variety of techniques and specialized facilities across the world. Nevertheless, most catastrophic earthquakes even
S. I. Sherman
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The cost of job displacement in Italy [PDF]
Administrative data from INPS (Italian Institute for Social Security) on Italian high tenure workers job-histories (15 years, from 1985 to 1999) is used to quantify the temporal pattern of the effect of displacement on workers’ earnings, employment and ...
Francesco Serti
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

