Results 81 to 90 of about 1,465,211 (311)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Infectious disease research in forcibly displaced populations: A systematic review in low- and middle-income host countries

Journal of Migration and Health
Background: Infectious disease research is essential for disease prevention and management within refugee camps and informal settlements. The objective of this study is to identify the characteristics of existing infectious disease research in these ...
Neila Gross, Maia C. Tarnas, Rashmina J. Sayeeda, Carly Ching, David Flynn, Muhammad H Zaman   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Researching health and internal displacement: Introduction to the special series

Journal of Migration and Health
This special series on ‘health and internal displacement’ is concerned primarily with the health needs of internally displaced persons (IDPs) in conflict contexts. Curated by editors from the recently established Health and Internal Displacement Network (
Jina Swartz, Bayard Roberts, David Cantor   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

“I left my country and the people I love. It gave me hypertension”: a qualitative study of social support and hypertension management in refugees

Frontiers in Public Health
BackgroundRefugees experience a disproportionately high burden of hypertension, with war-related displacement disrupting their social networks. Countries from the Middle East and North Africa (MENA) are among the largest producers of refugees globally ...
Ariana Khayamian, Carine Tamamian, Carine Tamamian, Lana Bridi, Alissa B. Sideman, Alissa B. Sideman, Nour Makarem, Dahlia A. Kaki, Tala Al-Rousan   +8 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Refugees and host communities’ vulnerability to climate and disaster risks in Rwanda

Frontiers in Climate
Climate change hazards pose significant risks to vulnerable populations, particularly refugees residing in camps within environmentally sensitive areas. This study assesses climate and disaster risks in refugee-hosting districts in Rwanda using GIS-based
Nfamara K. Dampha, Nfamara K. Dampha, Colette Salemi, Stephen Polasky, Stephen Polasky, Amare Gebre Egziabher, Wendy Rappeport   +6 more
doaj   +1 more source

Vision‐based multipoint displacement measurement for structural health monitoring

, 2016
A novel noncontact vision sensor for simultaneous measurement of structural displacements at multiple points using one camera is developed based on two advanced template matching techniques: the upsampled cross correlation (UCC) and the orientation code ...
Dongming Feng, M. Feng
semanticscholar   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source