Results 81 to 90 of about 2,189,086 (300)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Acupuncture and vitamin B12 injection for Bell′s palsy: no high-quality evidence exists

open access: yesNeural Regeneration Research, 2015
OBJECTIVE: To assess the efficacy of acupuncture combined with vitamin B 12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell′s palsy.
Li-li Wang   +4 more
doaj   +1 more source

Deformation Measurements at the Sub-Micron Size Scale: II. Refinements in the Algorithm for Digital Image Correction [PDF]

open access: yes, 1994
Improvements are proposed in the application of the Digital Image Correlation method, a technique that compares digital images of a specimen surface before and after deformation to deduce its sureface (2-D) displacement field and strains.
Knauss, W. G., Vendroux, G.
core  

A high stability optical shadow sensor with applications for precision accelerometers

open access: yes, 2017
Displacement sensors are found in a variety of applications including gravitational wave detectors, precision metrology, tissue imaging, gravimeters, microscopy, and environmental monitoring.
Bramsiepe, Steven G.   +4 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Infectious disease research in forcibly displaced populations: A systematic review in low- and middle-income host countries

open access: yesJournal of Migration and Health
Background: Infectious disease research is essential for disease prevention and management within refugee camps and informal settlements. The objective of this study is to identify the characteristics of existing infectious disease research in these ...
Neila Gross   +5 more
doaj   +1 more source

The Geography of ‘Otherness’: Spaces of Conflict in Smaro Kamboureli’s in the Second Person

open access: yesHumanities, 2019
In today’s “liquid” society, boundaries and limits are shifting or disorienting: belonging to no place, not knowing where ‘home’ is, underlines the sense of uncertainty and in-betweenness experienced by people.
Rocco De Leo
doaj   +1 more source

The Quantification of Tooth Displacement [PDF]

open access: yes, 2010
By using reference points from a single pixel marker placed at the center point of the cuspid teeth and the center point on each of the incisor teeth, a polynomial curve was generated as a native curve for each dental arch studied.
Johnson, L Thomas   +3 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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