Results 41 to 50 of about 183,763 (314)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Sudden stratospheric warmings (SSWs) can affect tropospheric weather and climate, while the factors affecting the surface response to SSWs are not fully understood.
Pengkun Yang, Ming Bao, Xuejuan Ren
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Previously, the author obtained an analytical solution for determining the vertical displacements of the homogeneous isotropic quarter-space face, which is affected by a vertical concentrated force.
S. V. Bosakov
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Performance Assessment of a Renovated Precast Concrete Bridge Using Static and Dynamic Tests
The article presents the development of a SHM (Structural Health Monitoring) strategy intended to confirm the improvement of the load-bearing capacity of a bridge over the Ružín Dam using static and dynamic load tests, as well as numerical simulations ...
Milan Sokol +3 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
ANALYSIS OF POINT CONTACTS USING THE COMBINED BOUSSINESQ-CERRUTI PROBLEM [PDF]
For "non-conforming" contact where deformations are small enough compared to body dimensions, the theoretical elasticity will apply to the closed contact defined by the contact area.The tension can be calculated by considering each body as a solid ...
Stefan GHIMISI
doaj

