Results 61 to 70 of about 95,850 (268)
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Observing the interactions between a social group : the young people, and spaces : the city and its political organisation, makes it possible to understand the impact of a local policy towards youth on their ways of moving in public space. The strategies
Véronique Bordes
doaj
Testing Multi-Frequency Low-Cost GNSS Receivers for Geodetic Monitoring Purposes
Global Navigation Satellite System (GNSS) technology is widely used for geodetic monitoring purposes. However, in cases where a higher risk of receiver damage is expected, geodetic GNSS receivers may be considered too expensive to be used.
Veton Hamza +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Displacement und Displaced Persons
Sebastian Huhn, Christoph Rass
openaire +2 more sources
Behaviour of unimorph ring-shaped piezoelectric actuator in fluidic valve
This article focuses on the behaviour analysis of an unimorph ring-shaped piezoelectric plate that is used as an actuator in a fluidic valve. First, the system modelling is discussed by using the material mechanical properties of the piezoelectric plate ...
XuDong Wang +3 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

