Results 61 to 70 of about 521,536 (306)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The influence of out-of-plane stress on a plane strain problem in rock mechanics [PDF]
This paper analyses the stresses and displacements in a uniformly prestressed Mohr-Coulomb continuum, caused by the excavation of an infinitely long cylindrical cavity.
Reed, M B
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Prediction of the anticlastic shape changes of hybrid composite material
In search of structurally better and aesthetically more attractive solutions of the erection of various structures, non‐standard anticlastic elements are used more frequently.
Andris Baikovs, Kārlis Rocēns
doaj
The links of high-speed mechanisms and manipulators are deformed under the action of inertia forces and external loads. These deformations have significantly influence on the accuracy of execution of the required law of motion by the operating point of
М. U. Utenov +2 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Static analysis and simplified design of suspension bridges having various rigidity of cables
Increased deformability can be considered as the basic disadvantage of suspension bridges. One of the ways to increase the rigidity of a suspension bridge is to transfer a part of stiffening girder rigidity to a suspension main cable.
Tatjana Grigorjeva +2 more
doaj
Analysis of Embedded Retaining Wall Using the Subgrade Reaction Method
This paper analyzes the distribution of internal forces and displacements of embedded retaining wall in Quaternary deposits and Tertiary clays. Calculations have been based on the Subgrade Reaction Method (SRM) for two different types of earth pressure ...
Pasik Tomasz +2 more
doaj +1 more source
Excitation of vibrational soft modes in disordered systems using active oscillation [PDF]
We propose a new method to characterize the spatial distribution of particles' vibrations in solids with much lower computational costs compared to the usual normal mode analysis.
72167 +3 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

