Results 51 to 60 of about 242,073 (299)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Static analysis and simplified design of suspension bridges having various rigidity of cables
Journal of Civil Engineering and Management, 2010 Increased deformability can be considered as the basic disadvantage of suspension bridges. One of the ways to increase the rigidity of a suspension bridge is to transfer a part of stiffening girder rigidity to a suspension main cable.
Tatjana Grigorjeva +2 more
doaj
Analysis of Embedded Retaining Wall Using the Subgrade Reaction Method
Studia Geotechnica et Mechanica, 2015 This paper analyzes the distribution of internal forces and displacements of embedded retaining wall in Quaternary deposits and Tertiary clays. Calculations have been based on the Subgrade Reaction Method (SRM) for two different types of earth pressure ...
Pasik Tomasz +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Malaysian Journal of International Relations, 2016 This article elucidates the ethical and methodological intricacies of the semi-structured interviews when the author conducted is qualitative-based fieldwork in the Internally Displaced Camps (IDPs) in Nairobi and Rift Valley, Kenya.
Muhammad Danial Azman
doaj +1 more source
Vertical displacements for various values of K0: (a) Vertical displacements; (b) Peak displacements.
Vertical displacements for various values of K0: (a) Vertical displacements; (b) Peak displacements.
Zhenbo Zhang (579190) +7 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Corrugated Shell Displacements During the Passage of a Vehicle Along a Soil-Steel Structure
Studia Geotechnica et Mechanica, 2016 Corrugated steel plates are highly rigid and as the constructions can be immersed in soil, they can be used as soil-steel structures. With an increase of cover depth, the effectiveness of operating loads decreases.
Machelski Czesław, Mumot Marcin
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Kinematic Convexity of Rigid Body Displacements
, 2010 In this paper, we explore the notion of kinematic convexity for rigid body displacements. Previously, we have shown that when spatial rigid body displacements are represented by dual quaternions, an oriented projective space is better suited for the ...
Jeff Ge, Anurag Purwar
core +1 more source