Results 51 to 60 of about 183,763 (314)
This article analyzes the ‘Hay inclined plane’ designed by the English engineer and entrepreneur William Reynolds and put into operation in 1792 to facilitate the transport of vessels between channels at different levels using an inclined ...
José Ignacio Rojas-Sola +1 more
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Diagnostics and assessment of the structural performance of collectors and tunnels require multi-criteria as well as comprehensive analyses for improving the safety based on acquired measurement data.
Paweł Popielski +5 more
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Pontian Hellenism in continuous “exodus” – prosfygia. Testimonies and interviews
Hellenism, established on the shores of the Black Sea (Greek Pontus) since ancient times (8th century BC colonization), preserved the Greek language and the Greek Spirit.
Georgia I. Charitidou
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Longâ€term strength and deformational analysis of reinforced concrete columns
The paper presents a method of nonâ€linear analysis of loadâ€carrying capacity and deformations of reinforced concrete columns subjected to longâ€term loads. Physical relationships expressing nonâ€linear relations between internal forces and stresses,
Valery Simbirkin, Robertas BaleviÄius
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Prediction of the anticlastic shape changes of hybrid composite material
In search of structurally better and aesthetically more attractive solutions of the erection of various structures, non‐standard anticlastic elements are used more frequently.
Andris Baikovs, Kārlis Rocēns
doaj
The links of high-speed mechanisms and manipulators are deformed under the action of inertia forces and external loads. These deformations have significantly influence on the accuracy of execution of the required law of motion by the operating point of
М. U. Utenov +2 more
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