Results 71 to 80 of about 242,073 (299)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Bridging Attitudes and Evidence: Climate Change Perspectives in Italy

open access: yesChallenges
The most visible and well-known consequence of natural and environmental disasters is displacement. The paper analyzes environmentally induced displacement and attitudes towards climate change in Italy between 2013 and 2023.
Alessandro Indelicato   +3 more
doaj   +1 more source

Joint Displacements in Linkage Synthesis Solutions

open access: yes, 1979
A comprehensive and unified treatment of the relationship between the displacements, about the joints of a four-bar linkage as it moves through specified design positions is given.
R. T. Strong, K. J. Waldron
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Les effets d’une politique municipale sur les déplacements des jeunes. Une approche socio-ethnographique

open access: yesSociétés et Jeunesses en Difficulté, 2008
Observing the interactions between a social group : the young people, and spaces : the city and its political organisation, makes it possible to understand the impact of a local policy towards youth on their ways of moving in public space. The strategies
Véronique Bordes
doaj  

Behaviour of unimorph ring-shaped piezoelectric actuator in fluidic valve

open access: yesThe Journal of Engineering, 2018
This article focuses on the behaviour analysis of an unimorph ring-shaped piezoelectric plate that is used as an actuator in a fluidic valve. First, the system modelling is discussed by using the material mechanical properties of the piezoelectric plate ...
XuDong Wang   +3 more
doaj   +1 more source

Testing Multi-Frequency Low-Cost GNSS Receivers for Geodetic Monitoring Purposes

open access: yesSensors, 2020
Global Navigation Satellite System (GNSS) technology is widely used for geodetic monitoring purposes. However, in cases where a higher risk of receiver damage is expected, geodetic GNSS receivers may be considered too expensive to be used.
Veton Hamza   +4 more
doaj   +1 more source

Vertical tunnel displacement for various bending stiffnesses: (a) Vertical displacements; (b) Peak displacements.

open access: yes
Vertical tunnel displacement for various bending stiffnesses: (a) Vertical displacements; (b) Peak displacements.
Zhenbo Zhang (579190)   +7 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Vertical tunnel displacement for various underpinning loads: (a) Vertical displacements; (b) Peak displacements.

open access: yes
Vertical tunnel displacement for various underpinning loads: (a) Vertical displacements; (b) Peak displacements.
Zhenbo Zhang (579190)   +7 more
core   +1 more source

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