Results 311 to 320 of about 750,066 (346)
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2012
Personalized medicine requires knowledge of factors influencing disease susceptibility and progression as well as effective treatments which minimize adverse drug reactions (ADRs). Surprisingly little attention has focused on the impact of sex on clinical therapeutics.
Amy C.M. Mattison Faye +1 more
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Personalized medicine requires knowledge of factors influencing disease susceptibility and progression as well as effective treatments which minimize adverse drug reactions (ADRs). Surprisingly little attention has focused on the impact of sex on clinical therapeutics.
Amy C.M. Mattison Faye +1 more
openaire +1 more source
Effect of phenobarbital on theophylline disposition
Journal of Allergy and Clinical Immunology, 1978The effect of chronic phenobarbital administration on the pharmacokinetics of theophylline was studied in 6 healthy, nonsmoking adults. Subject compliance was verified by the determination of plasma phenobarbital levels. Following four weeks of phenobarbital administration, all six subjects showed a resultant increase in serum clearance varying from 11%
R A, Landay, M A, Gonzalez, J C, Taylor
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Effect of Ranitidine on Chloroquine Disposition
Drug Intelligence & Clinical Pharmacy, 1987Ten healthy, male volunteers (aged 19–27 yr; weight 62–67 kg) were randomly distributed into control and test groups of five subjects each in a controlled study on the effect of ranitidine on chloroquine disposition. The control group subjects received two tablets of chloroquine sulfate (300-mg base) only.
E I, Ette, A, Brown-Awala, E E, Essien
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Effect of quinolones on caffeine disposition
Clinical Pharmacology and Therapeutics, 1989Six healthy volunteers received a single caffeine dose after pretreatment with norfloxacin, pipemidic acid, or placebo in a crossover, randomized, single-blind clinical trial. Quinolones altered the pharmacokinetics of caffeine, with a significant increase in the AUCs and a decrease in plasma clearance. The elimination half-life increased significantly
M, Carbó +4 more
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The Portfolio-Driven Disposition Effect
SSRN Electronic Journal, 2018In simple univariate tests, the disposition effect for a stock nearly disappears if the portfolio is at a gain. We find a large disposition effect when the portfolio is at a loss. The portfolio-driven disposition effect that we document is not explained by extreme returns, portfolio rebalancing, simultaneous transactions, or investor sophistication ...
Joseph Engelberg +2 more
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Symposium Drugs Effecting Cholesterol Disposition
1983Levels of plasma lipoproteins are regulated by the balance between their production and clearance. Although great attention has been paid to mechanisms for clearance of lipoproteins from plasma, work on factors regulating the production of lipoproteins has been limited.
S. M. Grundy +7 more
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The Portfolio‐Driven Disposition Effect
The Journal of FinanceABSTRACTThe disposition effect for a stock significantly weakens if the portfolio is at a gain, but is large when it is at a loss. We find this portfolio‐driven disposition effect (PDDE) in four independent settings: U.S. and Chinese archival data, as well as U.S. and Chinese experiments.
LI AN +4 more
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