Results 41 to 50 of about 2,381,058 (285)

Modelling the light-curves of objects tidally disrupted by a black hole

, 2009
Tidal disruption by massive black holes is a phenomenon, during which a large part of gravitational energy can be released on a very short time-scale. The time-scales and energies involved during X-ray and IR flares observed in Galactic centre suggest ...
A. Gomboc, A. Čadež, Carter, Carter, Gomboc, Laguna, Luminet, M. Calvani, U. Kostić, Čadež, Čadež, Calvani   +10 more
core   +1 more source

Quantitative Description of Digital Media

Journal of Quantitative Description: Digital Media, 2021
We introduce the rationale for a new peer-reviewed scholarly journal, the Journal of Quantitative Description: Digital Media. The journal is intended to create a new venue for research on digital media and address several deficiencies in the current ...
Kevin Munger, Andrew M. Guess, Eszter Hargittai   +2 more
doaj   +1 more source

Improved genome editing in human cell lines using the CRISPR method [PDF]

, 2014
The Cas9/CRISPR system has become a popular choice for genome editing. In this system, binding of a single guide (sg) RNA to a cognate genomic sequence enables the Cas9 nuclease to induce a double-strand break at that locus.
AW Briggs, C MacKay, Christophe Lachaud, F Zhang, Ivan M. Munoz, JL Schmid-Burgk, John Rouse, KS Makarova, KS Makarova, L Cong, M Jinek, P Mali, P Mali, PD Hsu, Piotr Szyniarowski, Rachel Toth, Stefan Maas, SW Cho, T Gaj, T Li, TJ Cradick, V Pattanayak, Y Fu   +22 more
core   +5 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome

Cell Death and Disease
Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, representing mature and immature-like Sertoli cells, and occasionally focal spermatogenesis.
Sofia B. Winge, Niels E. Skakkebaek, Lise Aksglaede, Gülizar Saritaş, Ewa Rajpert-De Meyts, Ellen Goossens, Anders Juul, Kristian Almstrup   +7 more
doaj   +1 more source

Butylated Hydroxyanisole (BHA) Disrupts Brain Signalling in Embryo–Larval Stage of Zebrafish Leading to Attention Deficit Hyperactivity Disorder (ADHD)

Journal of Xenobiotics
Background: Butylated hydroxyanisole (BHA) has been extensively used in several commercial industries as a preservative. It causes severe cellular and neurological damage affecting the developing fetus and might induce attention deficit hyperactivity ...
Kandhasamy Veshaal, Ramasamy Vasantharekha, Usha Rani Balu, Mahesh Vallabi Aayush, Saheshnu Sai Balaji Pillai, Winkins Santosh, Barathi Seetharaman   +6 more
doaj   +1 more source

Disruptive Technologies and the Law [PDF]

, 2014
In the past two decades, the concept of disruptive technology has gone from theory, to buzz word, to the captivation of the popular imagination. Disruptive innovation goes beyond improving existing products; it seeks to tap unforeseen markets, create ...
Katyal, Neal K.
core   +1 more source

SWIFT J164449.3+573451: a plunging event with the Poynting-flux dominated outflow

, 2012
Swift J164449+573451 is a peculiar outburst which is most likely powered by the tidal disruption of a star by a massive black hole. Within the tidal disruption scenario, we show that the periastron distance is considerably smaller than the disruption ...
Alexander, Alexander, Armitage, Ayal, Beloborodov, Blandford, Cannizzo, Cannizzo, Cummings, Fan, Fan, Fan, Gao, Kippenhahn, Lei, Lei, Levan, Li, Macdonald, MacFadyen, Popham, Shao, Thompson, Thorne, Usov, Wei-Hong Gao, Zhang, Zhang, Zhang   +28 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source