Results 21 to 30 of about 1,077,984 (269)

The Application of Principal Component Analysis on Clinical and Biochemical Parameters Exemplified in Children With Congenital Adrenal Hyperplasia

Frontiers in Endocrinology, 2021
PurposePrincipal component analysis (PCA) is a mathematical model which simplifies data into new, combined variables. Optimal treatment of pediatric congenital adrenal hyperplasia (CAH) remains a challenge and requires evaluation of all biochemical and ...
Marie Lindhardt Ljubicic, Marie Lindhardt Ljubicic, Andre Madsen, Andre Madsen, Andre Madsen, Anders Juul, Anders Juul, Kristian Almstrup, Kristian Almstrup, Trine Holm Johannsen, Trine Holm Johannsen   +10 more
doaj   +1 more source

In vitro investigation of endocrine disrupting effects of pesticides on Ca2+-signaling in human sperm cells through actions on the sperm-specific and steroid-activated CatSper Ca2+-channel

Environment International, 2022
Background: Ca2+-signaling controls sperm cell functions necessary for successful fertilization. Multiple endocrine disrupting chemicals have been found to interfere with normal Ca2+-signaling in human sperm cells through an activation of the sperm ...
Michala R. Birch, Mathias Johansen, Niels E. Skakkebæk, Anna-Maria Andersson, Anders Rehfeld   +4 more
doaj   +1 more source

Non-Classic Congenital Adrenal Hyperplasia in Two Adolescents With Gender Dysphoria

Journal of Psychosexual Health, 2021
The care of transgender individuals is multidisciplinary including medical, surgical, psychiatric, and psychological health professionals. We here report 2 cases of nonclassic congenital adrenal hyperplasia (CAH) coincidently discovered during the ...
Emma Wall, Lise Aksglaede, Mette Ewers Haahr, Peter Christiansen, Katharina M. Main   +4 more
doaj   +1 more source

Exploring the endocrine activity of air pollutants associated with unconventional oil and gas extraction

Environmental Health, 2018
Background In the last decade unconventional oil and gas (UOG) extraction has rapidly proliferated throughout the United States (US) and the world. This occurred largely because of the development of directional drilling and hydraulic fracturing which ...
Ashley L. Bolden, Kim Schultz, Katherine E. Pelch, Carol F. Kwiatkowski   +3 more
doaj   +1 more source

Levels of endocrine-disrupting chemicals are associated with changes in the peri-pubertal epigenome

Endocrine Connections, 2020
Puberty marks a transition period, which leads to the attainment of adult sexual maturity. Timing of puberty is a strongly heritable trait. However, large genetic association studies can only explain a fraction of the observed variability and striking ...
Kristian Almstrup, Hanne Frederiksen, Anna-Maria Andersson, Anders Juul   +3 more
doaj   +1 more source

Exposure to 15 phthalates and two substitutes (DEHTP and DINCH) assessed in trios of infants and their parents as well as longitudinally in infants exclusively breastfed and after the introduction of a mixed diet

Environment International, 2022
Objective: Several phthalates have been restricted/banned due to their adverse endocrine disrupting properties. The use of other phthalates and substitutes has increased.
Hanne Frederiksen, Emmie N. Upners, Marie Lindhardt Ljubicic, Margit Bistrup Fischer, Alexander Siegfried Busch, Casper P. Hagen, Anders Juul, Anna-Maria Andersson   +7 more
doaj   +1 more source

AMH and other markers of ovarian function in patients with Turner syndrome – a single center experience of transition from pediatric to gynecological follow up

Frontiers in Endocrinology, 2023
Turner syndrome (TS) is a chromosomal disorder that affects about 1 in 2500 female births and is characterized by the partial or complete absence of the second X chromosome. Depending on karyotype, TS is associated with primary ovarian insufficiency (POI)
Casper P. Hagen, Casper P. Hagen, Margit Bistrup Fischer, Margit Bistrup Fischer, Gylli Mola, Gylli Mola, Theis Bech Mikkelsen, Theis Bech Mikkelsen, Line Hartvig Cleemann, Line Hartvig Cleemann, Claus Højbjerg Gravholt, Claus Højbjerg Gravholt, Mette H. Viuff, Anders Juul, Anders Juul, Anders Juul, Anette Tønnes Pedersen, Katharina Maria Main, Katharina Maria Main, Katharina Maria Main   +19 more
doaj   +1 more source

Protecting and Expanding Railway Networks to Hedge against Disruptions: A Model with Travel Segments

Journal of Advanced Transportation, 2022
Railway systems are instrumental to countries’ economies. They are also vulnerable to man-made and natural disruptions and therefore need to be protected.
Stefano Starita, Chandra Ade Irawan, Pavitra Jindahra   +2 more
doaj   +1 more source

Reproductive hormones, bone mineral content, body composition, and testosterone therapy in boys and adolescents with Klinefelter syndrome

Endocrine Connections, 2023
Adult patients with Klinefelter syndrome (KS) are characterized by a highly variable phenotype, including tall stature, obesity, and hypergonadotropic hypogonadism, as well as an increased risk of developing insulin resistance, metabolic syndrome, and ...
Hans Valdemar López Krabbe, Jørgen Holm Petersen, Louise Laub Asserhøj, Trine Holm Johannsen, Peter Christiansen, Rikke Beck Jensen, Line Hartvig Cleemann, Casper P Hagen, Lærke Priskorn, Niels Jørgensen, Katharina M Main, Anders Juul, Lise Aksglaede   +12 more
doaj   +1 more source

A disruptive sequencer meets disruptive publishing [PDF]

F1000Research, 2015
Nanopore sequencing was recently made available to users in the form of the Oxford Nanopore MinION. Released to users through an early access programme, the MinION is made unique by its tiny form factor and ability to generate very long sequences from single DNA molecules.
Nick Loman, Sarah Goodwin, Hans J. Jansen, Matt Loose   +3 more
openaire   +2 more sources