Results 41 to 50 of about 2,114,322 (282)

Colocalization of protein kinase A with adenylyl cyclase enhances protein kinase A activity during induction of long-lasting long-term-potentiation. [PDF]

PLoS Computational Biology, 2011
The ability of neurons to differentially respond to specific temporal and spatial input patterns underlies information storage in neural circuits. One means of achieving spatial specificity is to restrict signaling molecules to particular subcellular ...
Myungsook Kim, Alan Jung Park, Robbert Havekes, Andrew Chay, Leonardo Antonio Guercio, Rodrigo Freire Oliveira, Rodrigo Freire Oliveira, Ted Abel, Kim T Blackwell   +8 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Dynamical and Statistical Indicators for Fusion Plasma Disruption Prediction

, 2023
Dynamical and Statistical Indicators for Fusion Plasma Disruption ...
Murari A, Craciunescu T
core  

High-beta disruption prediction study on HL-2A with instance-based transfer learning

Nuclear Fusion
Unmitigated disruptions pose a much more serious threat when large-scale tokamaks are operating in the high performance regime. Machine learning based disruption predictors can exhibit impressive performance.
Y. Zhong, W. Zheng, Z.Y. Chen, W. Yan, F. Xia, L.M. Yu, F.M. Xue, C.S. Shen, X.K. Ai, Z.Y. Yang, Y.L. Yu, Z.S. Nie, Y.H. Ding, Y.F. Liang, Z.P. Chen, J-TEXT Team   +15 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Design and development of an off-normal warning system for SPARC

Nuclear Fusion
The SPARC tokamak is a compact, high-field, and high-current device that will rely on disruption mitigation and prevention strategies to address the risks associated with its high stored energy densities.
A.R. Saperstein, C. Rea, R. Sweeney, M.D. Boyer, G.L. Trevisan, Y. Wei, the MIT PSFC Disruptions Team   +6 more
doaj   +1 more source

Study on Mechanism of Factors Affecting Resilience of Prefabricated Building Supply Chain

Advances in Civil Engineering, 2023
Identifying key factors affecting the resilience of a prefabricated building supply chain and exploring the effect mechanism of these factors can help to improve the resilience of the prefabricated building supply chain.
Chi Zhang, Kun He, Wenjie Zhang, Ting Jin, Yibin Ao   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Better, worse, or different than expected: on the role of value and identity prediction errors in fear memory reactivation

Scientific Reports, 2022
Although reconsolidation-based interventions constitute a promising new avenue to treating fear and anxieties disorders, the success of the intervention is not guaranteed.
A. M. V. Gerlicher, S. A. Verweij, M. Kindt   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source