Results 51 to 60 of about 407,221 (296)

Evaluating Descriptive Metrics of the Human Cone Mosaic [PDF]

open access: yes, 2016
Purpose: To evaluate how metrics used to describe the cone mosaic change in response to simulated photoreceptor undersampling (i.e., cell loss or misidentification).
Carroll, Joseph   +3 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Design and development of an off-normal warning system for SPARC

open access: yesNuclear Fusion
The SPARC tokamak is a compact, high-field, and high-current device that will rely on disruption mitigation and prevention strategies to address the risks associated with its high stored energy densities.
A.R. Saperstein   +6 more
doaj   +1 more source

Anticipating Railway Operation Disruption Events Based on the Analysis of Discrete-Event Diagnostic Data

open access: yesChemical Engineering Transactions, 2013
Public transport reliability is a highly important factor affecting passenger service quality, transportation mode choice, and operating costs. Unreliable service increases operating costs and reduces patronage.
O. Fink, E. Zio, U. Weidmann
doaj   +1 more source

Globally disruptive events show predictable timing patterns [PDF]

open access: yesInternational Journal of Astrobiology, 2016
AbstractGlobally disruptive events include asteroid/comet impacts, large igneous provinces and glaciations, all of which have been considered as contributors to mass extinctions. Understanding the overall relationship between the timings of the largest extinctions and their potential proximal causes remains one of science's great unsolved mysteries ...
Michael Gillman, Hilary E. Erenler
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Real-time data-driven disruption prediction and its mitigation of MA-plasma experiments in KSTAR with a lower carbon divertor

open access: yesNuclear Fusion
Real-time disruption prediction and its mitigation of mega-ampere (MA) plasma experiments have been performed in the 2022 KSTAR carbon lower divertor condition.
Jeongwon Lee   +7 more
doaj   +1 more source

Determining the nature of white dwarfs from low-frequency gravitational waves

open access: yes, 2018
An extreme-mass-ratio system composed of a white dwarf (WD) and a massive black hole can be observed by the low-frequency gravitational wave detectors, such as the Laser Interferometer Space Antenna (LISA). When the mass of the black hole is around $10^4
Fan, Xi-Long, Han, Wen-Biao
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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