Results 51 to 60 of about 2,114,322 (282)

Enhancing Disruption Prediction through Bayesian Neural Network in KSTAR

, 2023
Disruption in tokamak plasmas, stemming from various instabilities, poses a critical challenge, resulting in detrimental effects on the associated devices. Consequently, the proactive prediction of disruptions to maintain stability emerges as a paramount
Lee, Jeongwon, Na, Yong-Su, Seo, Jaemin, Kim, Jinsu, Ghim, Young-Chul, Lee, Yeongsun   +5 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Kamin blocking is associated with reduced medial-frontal gyrus activation: implications for prediction error abnormality in schizophrenia. [PDF]

PLoS ONE, 2012
The following study used 3-T functional magnetic resonance imaging (fMRI) to investigate the neural signature of Kamin blocking. Kamin blocking is an associative learning phenomenon seen where prior association of a stimulus (A) with an outcome blocks ...
Paula M Moran, Jennifer L Rouse, Benjamin Cross, Rhiannon Corcoran, Martin Schürmann   +4 more
doaj   +1 more source

Vi-DP: low-latency video-based disruption prediction with multi-FOV fusion in EAST

Nuclear Fusion
Plasma disruption poses a significant safety challenge for future tokamaks and fusion reactors. Prior work on disruption prediction relies primarily on multiple scalar zero-dimensional (0D) signals and one-dimensional (1D) profiles as input of the ...
M.W. Chen, K.J. Yang, J.J. Zhu, Q.J. Wang, F. Cheng, D.L. Chen, X.Z. Gong, B. Zhang, X.H. Zhang, Y.M. Duan, B.F. Gao, Y. Wang, W. Wang, Z.F. Guan, R.Z. Chen   +14 more
doaj   +1 more source

Anticipating Railway Operation Disruption Events Based on the Analysis of Discrete-Event Diagnostic Data

Chemical Engineering Transactions, 2013
Public transport reliability is a highly important factor affecting passenger service quality, transportation mode choice, and operating costs. Unreliable service increases operating costs and reduces patronage.
O. Fink, E. Zio, U. Weidmann
doaj   +1 more source

A Computational Model Predicting Disruption of Blood Vessel Development

PLoS Computational Biology, 2013
Vascular development is a complex process regulated by dynamic biological networks that vary in topology and state across different tissues and developmental stages. Signals regulating de novo blood vessel formation (vasculogenesis) and remodeling (angiogenesis) come from a variety of biological pathways linked to endothelial cell (EC) behavior ...
Nicole C. Kleinstreuer, David Dix, Michael Rountree, Nancy Baker 0001, Nisha Sipes, David M. Reif, Richard Spencer, Thomas Knudsen   +7 more
openaire   +5 more sources

Experimental Evaluation of Vitellogenin as a Predictive Biomarker for Reproductive Disruption [PDF]

Environmental Health Perspectives, 2001
Vitellogenin (VTG) synthesis in male oviparous vertebrates is used as an indicator of environmental estrogen exposure, but the relationship between elevated VTG levels and the effects of environmental estrogens on reproductive success are poorly understood.
Cheek, A.O., Brouwer, T.H., Carroll, S., Manning, S., McLachlan, J.A., Brouwer, M.   +5 more
openaire   +5 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source