Results 31 to 40 of about 140,191 (290)

Disruption of ribosome biogenesis triggers a p21/p53-mediated cell cycle checkpoint [PDF]

, 2006
Cell cycle entry requires a dramatic increase in protein production. In order to cope with this demand, the cell must upregulate ribosome biogenesis. Given that ribosome biogenesis is the most energy-consuming anabolic process in a growing cell, and ...
Di Cara, Alessandro
core   +1 more source

Using LSTM for the Prediction of Disruption in ADITYA Tokamak

CoRR, 2020
Major disruptions in tokamak pose a serious threat to the vessel and its surrounding pieces of equipment. The ability of the systems to detect any behavior that can lead to disruption can help in alerting the system beforehand and prevent its harmful effects. Many machine learning techniques have already been in use at large tokamaks like JET and ASDEX,
Aman Agarwal, Aditya Mishra, Priyanka Sharma, Swati Jain, Sutapa Ranjan, Ranjana Manchanda   +5 more
openaire   +2 more sources

Maternal Characteristics Predicting Young Girls' Disruptive Behavior [PDF]

Journal of Clinical Child & Adolescent Psychology, 2011
Little is known about the relative predictive utility of maternal characteristics and parenting skills on the development of girls' disruptive behavior. The current study used five waves of parent- and child-report data from the ongoing Pittsburgh Girls Study to examine these relationships in a sample of 1,942 girls from age 7 to 12 years. Multivariate
Molen, E. van der, Hipwell, A.E., Vermeiren, R., Loeber, R.   +3 more
openaire   +5 more sources

β-microglobulin amyloid fibril-induced membrane disruption is enhanced by endosomal lipids and acidic pH [PDF]

, 2014
Although the molecular mechanisms underlying the pathology of amyloidoses are not well understood, the interaction between amyloid proteins and cell membranes is thought to play a role in several amyloid diseases. Amyloid fibrils of β-microglobulin (βm),
Eric W. Hewitt, Xue, W-F, Beales Paul A., Sheynis, T, Radford, SE, Neil A. Ranson (610030), Sheena E. Radford (197775), Beales, Paul A, Goodchild Sophia C., Thompson, Rebecca, Xue Wei-Feng, Neil A. Ranson, Thompson Rebecca, Sheena E Radford, Sophia C. Goodchild, Sheynis Tania, Eric W Hewitt, Kevin W. Tipping (610028), Radford Sheena E., Tipping Kevin W., Sheena E. Radford, Hewitt, EW, Xue, Wei-Feng, Beales, PA, Radford, Sheena E, Tipping, KW, Sophia C Goodchild, Paul A Beales, Goodchild, SC, Ranson, Neil A, Rebecca Thompson, Wei-Feng Xue (610029), Ranson Neil A., Neil A Ranson, Tipping, Kevin W, Tania Sheynis (610026), Kevin W Tipping, Tania Sheynis, Sheynis, Tania, Wei-Feng Xue, Goodchild, Sophia C, Eric W. Hewitt (197779), Hewitt, Eric W, Hewitt Eric W., Sophia C. Goodchild (283440), Ranson, NA, Rebecca Thompson (610027), Paul A. Beales (435545), Thompson, R, Paul A. Beales   +49 more
core   +1 more source

Design of Real-Time Data Acquisition System for Tokamak Disruption Prediction

南方能源建设
[Introduction] Plasma disruption poses a significant threat to the tokamak nuclear device during its running and can cause damage to the device. Such damage can be reduced by adopting the disruption mitigation system, which has an action time highly ...
Peilong ZHANG, Weijie YE, Wei ZHENG, Yonghua DING, Liye WANG, Yulin YANG   +5 more
doaj   +1 more source

Colocalization of protein kinase A with adenylyl cyclase enhances protein kinase A activity during induction of long-lasting long-term-potentiation. [PDF]

PLoS Computational Biology, 2011
The ability of neurons to differentially respond to specific temporal and spatial input patterns underlies information storage in neural circuits. One means of achieving spatial specificity is to restrict signaling molecules to particular subcellular ...
Myungsook Kim, Alan Jung Park, Robbert Havekes, Andrew Chay, Leonardo Antonio Guercio, Rodrigo Freire Oliveira, Rodrigo Freire Oliveira, Ted Abel, Kim T Blackwell   +8 more
doaj   +1 more source

Tungsten melting and erosion under plasma heat load in tokamak discharges with disruptions

Nuclear Materials and Energy, 2017
Full tungsten poloidal and mushroom limiters were tested in series of experiments with disruptions in the T-10 tokamak. Significant melting, formation of small craters and erosion of the tungsten limiter have been observed after ∼400 discharges with ...
V.P. Budaev, Yu.V. Martynenko, S.A. Grashin, R.N. Giniyatulin, I.I. Arkhipov, A.V. Karpov, P.V. Savrukhin, E.A. Shestakov, R.Yu. Solomatin, L.B. Begrambekov, N.E. Belova, S.D. Fedorovich, L.N. Khimchenko, V.M. Safronov   +13 more
doaj   +1 more source

Study on Mechanism of Factors Affecting Resilience of Prefabricated Building Supply Chain

Advances in Civil Engineering, 2023
Identifying key factors affecting the resilience of a prefabricated building supply chain and exploring the effect mechanism of these factors can help to improve the resilience of the prefabricated building supply chain.
Chi Zhang, Kun He, Wenjie Zhang, Ting Jin, Yibin Ao   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Better, worse, or different than expected: on the role of value and identity prediction errors in fear memory reactivation

Scientific Reports, 2022
Although reconsolidation-based interventions constitute a promising new avenue to treating fear and anxieties disorders, the success of the intervention is not guaranteed.
A. M. V. Gerlicher, S. A. Verweij, M. Kindt   +2 more
doaj   +1 more source