Results 21 to 30 of about 59,050 (253)

Responding to the ripple effect from systemic disruptions: empirical evidence from the semiconductor shortage during COVID-19 [PDF]

Modern Supply Chain Research and Applications
Purpose – The ripple effect (i.e. disruption propagation in networks) belongs to one of the central pillars in supply chain resilience and viability research, constituting a type of systemic disruption. A considerable body of knowledge has been developed
Kateryna Kravchenko, Tim Gruchmann, Marina Ivanova, Dmitry Ivanov   +3 more
doaj   +1 more source

Author Correction: Empirical dynamics of railway delay propagation identified during the large-scale Rastatt disruption

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Beda Büchel, Thomas Spanninger, Francesco Corman   +2 more
doaj   +1 more source

Blood–brain barrier disruption results in delayed functional and structural alterations in the rat neocortex

Neurobiology of Disease, 2007
Disruption of the blood–brain barrier (BBB) is a characteristic finding in common neurological disorders. Human data suggest BBB disruption may underlie cerebral dysfunction.
O. Tomkins, O. Friedman, S. Ivens, C. Reiffurth, S. Major, J.P. Dreier, U. Heinemann, A. Friedman   +7 more
doaj   +1 more source

Supply Chain Disruption Models: A Critical Review

Logistics Research, 2018
Enterprises affected by supply chain disruptions have reported adverse consequences and dramatic financial losses. Within the research area of supply chain risk management, researchers use simulation models and algorithms to analyze disruption risks ...
Niels Bugert, Rainer Lasch
doaj   +1 more source

Pathological mechanisms of connexin26-related hearing loss: Potassium recycling, ATP-calcium signaling, or energy supply?

Frontiers in Molecular Neuroscience, 2022
Hereditary deafness is one of the most common human birth defects. GJB2 gene mutation is the most genetic etiology. Gap junction protein 26 (connexin26, Cx26) encoded by the GJB2 gene, which is responsible for intercellular substance transfer and signal ...
Penghui Chen, Penghui Chen, Penghui Chen, Wenjin Wu, Wenjin Wu, Wenjin Wu, Jifang Zhang, Jifang Zhang, Jifang Zhang, Junmin Chen, Junmin Chen, Junmin Chen, Yue Li, Yue Li, Yue Li, Lianhua Sun, Lianhua Sun, Lianhua Sun, Shule Hou, Shule Hou, Shule Hou, Jun Yang, Jun Yang, Jun Yang   +23 more
doaj   +1 more source

Pressure Wave Propagation Optimization Models for Supply Chain Risk Mitigation

Systems
Supply chain (SC) disruption risk assessment and mitigation have attracted significant attention in both academia and practice. However, existing research predominantly focuses on unidirectional disruption propagation, either forward or backward, despite
Ming Liu, Jiawei Zhang, Yueyu Ding
doaj   +1 more source

Multiplexity and Disruption Propagation in Global Container Liner Shipping Networks: From the Perspective of Carriers’ Geopolitical Affiliations

Entropy
Global container liner shipping networks (GCLSNs) underpin world trade, yet their organization is increasingly reshaped by geopolitical fragmentation. Existing studies often model GCLSNs as single-layer networks, overlooking how carriers’ geopolitical ...
Huanyu Ren, Xiaozhen Lian, Qiong Chen, Ziheng Lin, Zonghui Jiang, Zhenglong Li   +5 more
doaj   +1 more source

Propagation of Uncertain Events in Multilevel Handlings at Container Terminals from the Perspective of Hypernetwork

Discrete Dynamics in Nature and Society, 2021
Due to the complexity and dynamics of container terminal multilevel handlings, the occurrence of uncertain events often leads to the disruption of many operation plans and forms a chain reaction, resulting in economic losses and impacts.
Bowei Xu, Lingling Wang, Junjun Li
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source