Results 41 to 50 of about 183,323 (251)

A mathematical model for persistent post-CSD vasoconstriction.

PLoS Computational Biology, 2020
Cortical spreading depression (CSD) is the propagation of a relatively slow wave in cortical brain tissue that is linked to a number of pathological conditions such as stroke and migraine.
Shixin Xu, Joshua C Chang, Joshua C Chang, Carson C Chow, K C Brennan, Huaxiong Huang   +5 more
doaj   +1 more source

Towards the azimuthal characteristics of ionospheric and seismic effects of "Chelyabinsk" meteorite fall according to the data from coherent radar, GPS and seismic networks

, 2015
We present the results of a study of the azimuthal characteristics of ionospheric and seismic effects of the meteorite 'Chelyabinsk', based on the data from the network of GPS receivers, coherent decameter radar EKB SuperDARN and network of seismic ...
Bakhtiyarov, V. F., Berngardt, O. I., Dobrynina, A. A., Kusonsky, O. A., Kutelev, K. A., Perevalova, N. P., Shestakov, N. V., Zagretdinov, R. V., Zherebtsov, G. A.   +8 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Computational and in vitro studies of blast-induced blood-brain barrier disruption

, 2015
There is growing concern that blast-exposed individuals are at risk of developing neurological disorders later in life. Therefore, it is important to understand the dynamic properties of blast forces on brain cells, including the endothelial cells that ...
Banks, William A., Cook, David G., Del Razo, Mauricio J., Huber, B. Russell, Leveque, Randall J., Meabon, James S., Morofuji, Yoichi, Mourad, Pierre D., Peskind, Elaine R.   +8 more
core   +1 more source

The Gaseous Environments of Radio Galaxies [PDF]

, 1999
X-ray emission traces the gaseous environments of radio sources. The medium must be present for jet confinement, but what are its influence on jet fuelling, dynamics, propagation, and disruption?
Allen, Allen, Arnaud, Arnaud, Barthel, Birkinshaw, Bliton, Boella, Bremer, Brunetti, Böhringer, Canosa, Carilli, Ciotti, Colla, Crawford, D.M Worrall, Fabbiano, Fabbiano, Fanaroff, Feigelson, Feigelson, Feretti, Ferrarese, Hardcastle, Hardcastle, Hardcastle, Hardcastle, Hardcastle, Hardcastle, Harris, Killeen, Laing, Leahy, Matsumoto, Miller, Morganti, Owen, O’Dea, O’Dea, Reynolds, Sakelliou, Sambruna, Schreier, Tashiro, Trussoni, Trussoni, Tsakiris, Ueno, Ulrich, Werner, Worrall, Worrall, Worrall, Worrall, Worrall   +55 more
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The Disruption of Geniculocalcarine Tract in Occipital Neoplasm: A Diffusion Tensor Imaging Study

Radiology Research and Practice, 2016
Aim. Investigate the disruption of geniculocalcarine tract (GCT) in different occipital neoplasm by diffusion tensor imaging (DTI). Methods. Thirty-two subjects (44.1 ± 3.6 years) who had single occipital neoplasm (9 gliomas, 6 meningiomas, and 17 ...
Yan Zhang, Sihai Wan, Ge Wen, Xuelin Zhang   +3 more
doaj   +1 more source

Tweeting Behaviour during Train Disruptions within a City [PDF]

, 2015
In a smart city environment, citizens use social media for communicating and reporting events. Existing work has shown that social media tools, such as Twitter and Facebook, can be used as social sensors to monitor events in real-time as they happen (e.
Albakour, M-Dyaa, Limsopatham, Nut, Macdonald, Craig, Ounis, Iadh   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Modeling Disruption Tolerance Mechanisms for a Heterogeneous 5G Network

IEEE Access, 2018
Delay/disruption tolerant networking (DTN) was proposed as an internetworking architecture to accommodate the frequent and lengthy link disruptions and/or long propagation delays that are typical of a challenging communication environment.
Ruhai Wang, Alaa Sabbagh, Scott C. Burleigh, Mahjabeen Javed, Shushi Gu, Jian Jiao, Qinyu Zhang   +6 more
doaj   +1 more source