Results 51 to 60 of about 59,050 (253)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Indirect mapping of the source of the oppositely directed fast plasma flows in the plasma sheet onto the auroral display [PDF]

Annales Geophysicae, 2006
Data from Polar and Geotail spacecraft are combined to investigate the relationship between locations of active auroras and the magnetotail plasma sheet region where reversed fast plasma flows are generated during substorms.
A. G. Yahnin, I. V. Despirak, A. A. Lubchich, B. V. Kozelov, N. P. Dmitrieva, M. A. Shukhtina, H. K. Biernat   +6 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Tracing the propagation of disruptions in supply chain scenarios: A case study of photovoltaics diversification

Resources, Conservation and Recycling
Diversifying supply chains through reshoring and friendshoring is increasingly proposed as a key strategy for supply security and resilience. Quantitative analyses characterizing to what extend diversification shield countries from supply disruptions remain however scarce.
Estelle Gervais, Benjamin Sprecher, Sebastian Nold, Peter Brailovsky, René Kleijn   +4 more
openaire   +2 more sources

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Driver Behavior-Driven Evacuation Strategy with Dynamic Risk Propagation Modeling for Road Disruption Incidents

Eng
When emergency incidents, such as bridge damage, abruptly occur on highways and lead to traffic disruptions, the multidimensionality and complexity of driver behaviors present significant challenges to the design of effective emergency response ...
Yanbin Hu, Wenhui Zhou, Hongzhi Miao
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Conditional recovery of time-reversal symmetry in many nucleus systems

New Journal of Physics, 2019
The propagation of non-topological solitons in many-nucleus systems is studied based on time-dependent density functional calculations, focusing on mass and energy dependence.
Yoritaka Iwata, Paul Stevenson
doaj   +1 more source

Supply chain disruption propagation: a systemic risk and normal accident theory perspective

International Journal of Production Research, 2017
When a disruption occurs in a firm, its effects are often felt throughout the supply chain. As supply chains expand globally and companies pursue velocity and efficiency, the probability of disruptions propagating throughout a chain grows. In this paper, we employ a qualitative, grounded theory case study approach to help understand what drives supply ...
Kevin P. Scheibe, Jennifer Blackhurst
openaire   +3 more sources