Results 91 to 100 of about 185,290 (300)

Parenting interventions for ADHD: a systematic literature review and meta-analysis [PDF]

, 2015
Objective. To evaluate the evidence base relating to the effectiveness of parent-administered behavioral interventions for ...
Abidin R., American Psychiatric Association, American Psychiatric Association, Barkley R. A., Barkley R. A., Barkley R. A., Conners C. K., Eyberg S. M., Forehand R., Goldberg D., National Institute for Health and Clinical Excellence, Taylor E. A.   +11 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Teachers’ Strategies towards the Students’ Disruptive Behavior in Learning English

Jurnal Studi Guru dan Pembelajaran, 2019
This research aims at finding out the students’ disruptive behaviors in learning English and the teachers’ strategies toward students’ disruptive behavior in learning English. The sample of this research 4 teachers.
Reski Pilu, Purnama Cahya, Musfirah Musfirah   +2 more
doaj   +1 more source

HR: Innovation\u27s Accelerator [PDF]

, 2017
[Excerpt] Amazon and Borders. Netflix and Blockbuster. Uber and taxi drivers. Digital camera makers and Kodak. The list could go on and on. Individual stories of disruptive innovation such as these are some of the most well known - and ca utionary ...
Gaines, Janelle, Kanbergs, Mara, Sowards, Nick   +2 more
core   +1 more source

Desenho em série com meninas que apresentam comportamento oposicionista desafiante em sala de aula [PDF]

, 2015
Este estudio investigó las correlaciones entre la participación en sesiones terapéuticas de dibujo en serie, no dirigido, y la presencia o ausencia de mejoría en el comportamiento oposicionista desafiante (COD) de cinco niñas, de ocho a diez años de edad,
Boone-Salles, Andréia Mansk
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Sympathy for the Devil: Serial Mediation Models for Toxicity, Community, and Retention

Media and Communication
Disruptive behaviors in online gaming communities are a growing concern, affecting player experience, retention, and well-being. While previous research has primarily focused on the victims’ experiences, this study examines the psychological mechanisms ...
Mingxuan Liu, Jack Lipei Tang, Dmitri Williams   +2 more
doaj   +1 more source

Functional Analytic Psychotherapy among Mothers with Children with Disruptive Behavior

Clínica y Salud. Investigación Empírica en Psicología, 2018
Children’s mental problems remain one of the central topics in governments’ agendas because of their negative impact at social and economic levels. The present paper is a single case study, with A-B design with concurrent control through behaviors and ...
Johanna Romero-Porras, Diana Obando-Posada, Aldo Hernández-Barrios, Diana Velasco-Pinzón   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source