The MHD Kelvin-Helmholtz Instability III: The Role of Sheared Magnetic Field in Planar Flows [PDF]
, 1999 We have carried out simulations of the nonlinear evolution of the magnetohydrodynamic (MHD) Kelvin-Helmholtz (KH) instability for compressible fluids in $2\frac{1}{2}$-dimensions, extending our previous work by Frank et al (1996) and Jones \etal (1997 ...
Adam Frank +11 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
School Violence Prevention: Evaluating a Cognitive-Behavioral Intervention for Aggression Among Adolescents [PDF]
, 2020 Schools are held accountable for creating and maintaining safe learning environments for all students. The prevalence of behavior and conduct disorders, specifically aggression, remain problematic for school campuses.
Katic, Barbara
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Educate Every Child: Promoting Positive Solutions to School Discipline in Virginia [PDF]
, 2011 Explains how suspension and expulsion for minor misbehavior leads to lower achievement, higher dropout rates, and more contact with juvenile justice.
Angela A. Ciolfi +2 more
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10 Key Policies and Practices for Schoolwide and Classroom-Based Behavioral Supports With Strong Evidence of Effectiveness From High-Quality Research [PDF]
, 2017 The seventh installment of MCPER's "10 Key" series, this document distills the latest research findings into 10 easy-to-follow recommendations that states, school districts, and schools can use to improve schoolwide and classroom behavioral supports ...
The Meadows Center for Preventing Educational Risk
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Does computer-supported Math instruction makes students perceive them to be task-oriented and well-behaved? An experimental study [PDF]
, 1924 This study investigated the effectiveness of computer-supported Math instruction on ninth graders’ task orientation and disruptive behaviors. Subjects were 40 students enrolled in two classes, each of which was randomly selected as the experimental and ...
Koc, Mustafa, Erginbas, Senol
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Positive Behavior Support and Student Response to the Behavior Education Program [PDF]
, 2009 School-wide positive behavior supports (SWPBS) is an evidence-based systematic approach that views problem behaviors in a positive, preventative manner.
Paolella, Kate
core +1 more source