Results 121 to 130 of about 1,052,737 (342)

Disseminated Tuberculosis Following Total Knee Arthroplasty in an HIV Patient [PDF]

, 2018
Skeletal tuberculosis is now uncommon in developed countries. In immunocompromised patients - particularly in the HIV-infected - who present with subacute or chronic joint pain refractory to conventional treatment, osteoarticular tuberculosis should ...
Droz, S., Evison, J.-M, Marschall, J., Studer, U., Zimmerli, S.   +4 more
core  

Human tuberculosis - an ancient disease, as elucidated by ancient microbial biomolecules [PDF]

, 2009
Tuberculosis is a major cause of death but infected people with effective immunity may remain healthy for years, suggesting long-term coexistence of host and pathogen.
Donoghue, HD
core   +1 more source

Long‐term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium

British Journal of Haematology, EarlyView.
The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an
Flore Sicre de Fontbrune, Florian Chevillon, Mony Fahd, Kristell Desseaux, Xavier Poiré, Edouard Forcade, Arthur Sterin, Bénédicte Neven, Virginie Gandemer, Sylvain Thepot, Alice Garnier, Bruno Lioure, Ambroise Marcais, Stephanie Nguyen‐Quoc, Suzanne Tavitian, Laure Vincent, Jean Donadieu, Matthieu Resche Riggon, Sylvie Chevret, Marlene Pasquet, Regis Peffault de Latour   +20 more
wiley   +1 more source

Calvarial tuberculosis: an unusual presentation of disseminated tuberculosis

BMJ Case Reports, 2019
A 30-year-old man, without previous medical record, was admitted to our centre due to persistent hacking cough for the previous 2 months, accompanied by nocturnal sweating, unquantified weight loss and low-grade fever. The patient was finally diagnosed of pulmonary tuberculosis (TB).
Alfredo Manuel Santos Pinheiro da Silva Martins, Francisco Fanjul, Antoni Abdon Campins Rosselló, Melchor Riera Jaume   +3 more
openaire   +4 more sources

Disseminated tuberculosis with tuberculous meningitis in an immunocompetent host

Oxford Medical Case Reports, 2014
Disseminated tuberculosis (TB) results from the lymphohematogenous spread of Mycobacterium tuberculosis. Despite the availability of effective therapy, diagnosis is usually late and mortality remains high.
T. Hilal, P. Hurley, M. Mccormick
semanticscholar   +1 more source

Mechanism of cyanobacterial ferredoxin‐dependent flavin thioredoxin reductase reveals thiolate‐FAD charge transfer and catalytic asymmetry in a homodimer

The FEBS Journal, EarlyView.
Ferredoxin‐dependent flavin thioredoxin reductases (FFTRs) regenerate reduced thioredoxin, sustaining dithiol–disulfide exchange reactions that regulate protein activity in select organisms. In cyanobacterial FFTRs, we describe the formation of a thiolate–flavin charge transfer complex, asynchronous reduction of the two FAD cofactors within the ...
Martha Minjarez‐Saenz, Víctor Correa‐Pérez, Maribel Rivero, Alejandro Hernández‐Gómez, Marta Martínez‐Júlvez, Rubén M. Buey, Federico Gago, Monica Balsera, Milagros Medina   +8 more
wiley   +1 more source

Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis

Brazilian Journal of Infectious Diseases
Three HIV-1-seronegative patients with disseminated tuberculosis presented significant depletion of T-cell counts, in CD4+ and/or CD8+ cells, associated with increased expression of activation marker CD38 on CD8+ T-lymphocytes.
Denise Silva Rodrigues, Reinaldo Salomão, Esper Georges Kallas   +2 more
doaj   +1 more source

Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments

The FEBS Journal, EarlyView.
Gasdermins (GSDMs) are pore‐forming proteins best known for driving pyroptosis through plasma membrane (PM) permeabilization. Beyond triggering inflammatory cell death, GSDMs can also associate with organelle membranes, including mitochondria, lysosomes, ER, and nucleus, where they modulate membrane integrity and cellular signaling.
Eleonora Margheritis, Nadine Gehle, Katia Cosentino   +2 more
wiley   +1 more source

Concurrent multiple brain tuberculomas with miliary tuberculosis - A rare presentation

Asian Journal of Medical Sciences, 2014
A 45 year old immunocompetent female presented to us with fever, dry cough, vomitingand headache. There was a single episode of convulsion after hospital admission. ChestXray was normal.
Susmita Kundu
doaj   +1 more source

Multiple Bilateral Erythematous and Suppurative Cutaneous Nodules in a 40‐Year‐Old Indian Female

JEADV Clinical Practice, EarlyView.
Aditi Anand, Shaivy Malik, Charanjeet Ahluwalia   +2 more
wiley   +1 more source