Results 71 to 80 of about 219,079 (300)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Single spin universal Boolean logic

, 2008
Recent advances in manipulating single electron spins in quantum dots have brought us close to the realization of classical logic gates based on representing binary bits in spin polarizations of single electrons.
Amasha S, Amasha S, Bandyopadhyay S, deSousa R, H Agarwal, Keyes R W, Molotkov S N, Molotkov S N, Moore G E, S Bandyopadhyay, S Pramanik   +10 more
core   +1 more source

Neutrinos From Individual Gamma-Ray Bursts in the BATSE Catalog [PDF]

, 2003
We calculate the neutrino emission from individual gamma-ray bursts observed by the BATSE detector on the Compton Gamma-Ray Observatory. Neutrinos are produced by photoproduction of pions when protons interact with photons in the region where the kinetic
Alvarez-Muñiz, Andres, D. Guetta, D. Hooper, Dermer, Dutta, Dziewonski, E. Reuveni, Eichler, F. Halzen, Fishman, Freedman, Fryer, Fryer, Gaisser, Guetta, Guetta, Guetta, Guetta, Guetta, Halzen, Halzen, Halzen, Heise, Inoue, J. Alvarez-Muñiz, Kobayashi, Königl, Lazzati, Learned, Lloyd-Ronning, Norris, Paciesas, Paczński, Piro, Razzaque, Rees, Reichart, Reichart, Sari, Vietri, Vietri, Vietri, Vietri, Vietri, Vietri, Waxman, Waxman, Waxman, Woosley, Zhang   +50 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analysis of energy dissipation characteristics in granite under high confining pressure cyclic load

Alexandria Engineering Journal, 2020
With cyclic high in-situ stress, the rock will damage and lead to serious engineering geological disasters. A property of rock failure is the rock damage evolution driven by energy.
Dongjie Yang, Jianhua Hu, Xiaotian Ding
doaj   +1 more source

The influence of particle properties on pressure signals in dense gas-fluidised beds: a computer simulation study [PDF]

, 1998
A hard-sphere discrete particle model of a gas-fluidised bed was used in order to study the influence of particle properties on pressure signals in dense gasfluidised beds.
Hoomans, B.P.B., Kuipers, J.A.M., Swaaij, W.P.M. van   +2 more
core   +1 more source

Loose mechanochemical coupling of molecular motors

, 2011
In living cells, molecular motors convert chemical energy into mechanical work. Its thermodynamic energy efficiency, i.e. the ratio of output mechanical work to input chemical energy, is usually high.
Howard J., Oster G., Wang H., Yasuda R., YUNXIN ZHANG   +4 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An energy description of wear mechanisms and its applications to oscillating sliding contacts [PDF]

, 2003
To quantify wear rates, the Archard approach is classically applied. It relates the wear volume to the product of the sliding distance and the normal load.
Archard, Berthier, Bill, Dubourg, Farris, Fouvry, Fouvry, Fouvry, Fouvry, Godet, Hannel, Hoeppner, Johnson, Kapoor, Langlade, Liskiewicz, Meng, Mindlin, Mohrbacher, Nowell, Sauger, Vincent, Vingsbo   +22 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source