Results 81 to 90 of about 7,628,584 (339)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Trend Analysis of Dissipated Electrostatic Discharge Energy in Touchscreen Displays

open access: yes, 2020
Touchscreen displays can be susceptible to sparkless electrostatic discharge events. The energy observed by sensitive touchscreen circuitry can vary significantly with design parameters like the glass thickness, the capacitance between the sensor pad and
DongHyun Kim   +17 more
core   +1 more source

ENERGY DISSIPATION IN TIDAL ESTUARIES

open access: yesCoastal Engineering Proceedings, 1976
In this study, the method for damped co-oscillating tides is used to evaluate damping and energy dissipation characteristics for various estuaries of different geometry and depth. Of special interest are the damping and energy dissipation characteristics of the German tidal rivers such as Elbe, Weser and Ems in comparison with North-American tidal ...
Hans-Werner Partenscky, Günther Barg
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Wetlands as energy-dissipating systems

open access: yesJournal of Industrial Microbiology & Biotechnology, 2010
Since wetlands are ecosystems that have an ample supply of water, they play an important role in the energy budgets of their respective landscapes due to their capacity to shift energy fluxes in favor of latent heat. Rates of evapotranspiration in wetlands are commonly as high as 6-15 mm day⁻¹, testifying to the large amount of energy that is ...
Pokorný, J.   +3 more
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A self-regulated expiratory flow device for mechanical ventilation: a bench study

open access: yesIntensive Care Medicine Experimental
Introduction Unregulated expiratory flow may contribute to ventilator-induced lung injury. The amount of energy dissipated into the lungs with tidal mechanical ventilation may be used to quantify potentially injurious ventilation.
Lianye Yang   +6 more
doaj   +1 more source

Energy Evolution Characteristics and Distribution Laws of Rock Materials under Triaxial Cyclic Loading and Unloading Compression

open access: yesAdvances in Materials Science and Engineering, 2017
To explore the influence of confining pressure on the energy evolution characteristics of loaded rocks, triaxial cyclic loading-unloading experiments on sandstones were carried out under 6 kinds of confining pressures using the axial loading and ...
Mingwei Zhang   +2 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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