Results 91 to 100 of about 1,227,945 (330)

Developmental and attachment-based perspectives on dissociation: beyond the effects of maltreatment

open access: yesEuropean Journal of Psychotraumatology, 2020
Background: Numerous years of theory and research have informed our understanding of the caregiving experiences that confer vulnerability for dissociation.
Camille Guérin-Marion   +2 more
doaj   +1 more source

Femtosecond Photodissociation of Molecules Facilitated by Noise

open access: yes, 2007
We investigate the dynamics of diatomic molecules subjected to both a femtosecond mid-infrared laser pulse and Gaussian white noise. The stochastic Schr\"odinger equation with a Morse potential is used to describe the molecular vibrations under noise and
Anatole Kenfack   +3 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

The Harvard Beat Assessment Test (H-BAT): A Battery for Assessing Beat Perception and Production and their Dissociation

open access: yesFrontiers in Human Neuroscience, 2013
Humans have the abilities to perceive, produce, and synchronize with a musical beat, yet there are widespread individual differences. To investigate these abilities and to determine if a dissociation between beat perception and production exists, we ...
Shinya eFujii, Gottfried eSchlaug
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Head and Neck Positions Affect Equine Kinematic Variables in Marcha Batida Gait—A Pilot Study

open access: yesAnimals
The Mangalarga Marchador (MM) breed naturally performs four-beat gaits known as “Marcha”. Kinematic analysis can provide insights for optimizing training and competition performance in this breed while potentially mitigating welfare concerns associated ...
Natália Almeida Martins   +8 more
doaj   +1 more source

Dissociated Steroids [PDF]

open access: yesThe Scientific World JOURNAL, 2007
Glucocorticoids (GCs) are some of the most important drugs in clinical use today. They are mainly used to suppress disease-related inflammation and are widely used for the treatment of many inflammatory diseases including asthma and arthritis. However, GCs are also associated with debilitating side effects that place limitations on the long-term use of
openaire   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Sleep, trauma, fantasy and cognition in dissociative identity disorder, post-traumatic stress disorder and healthy controls: a replication and extension study

open access: yesEuropean Journal of Psychotraumatology, 2020
Background: Two aetiology models for dissociative identity disorder (DID) have been proposed, namely a childhood Trauma Model and an iatrogenic or Fantasy model.
Lora Dimitrova   +5 more
doaj   +1 more source

Stochastic dissociation of diatomic molecules

open access: yes, 2005
The fragmentation of diatomic molecules under a stochastic force is investigated both classically and quantum mechanically, focussing on their dissociation probabilities.
Kenfack, Anatole, Rost, Jan M
core   +1 more source

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