Results 71 to 80 of about 644,654 (317)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The relationship of dissociation to borderline and schizotypal personality syndromes [PDF]

open access: yes, 2001
Borderline and schizotypal personality constructs were compared as predictors of dissociation for 971 nonclinical university undergraduates who completed 11 self-report behavior inventories.
Stockdale, Gary D.
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Dissociative symptoms and the quality of structural integration in borderline personality disorder [PDF]

open access: yes, 2014
Background Transient dissociation is a core feature of borderline personality disorder (BPD). Dissociation is characterized by detachment from reality, which can be mild (e.g. daydreaming) to severe (e.g. depersonalization, amnesia).
Sole, S
core  

Psychodynamic Insights and Approach to a Case of Dissociative Identity Disorder

open access: yesJournal of the Scientific Society
Dissociative identity disorder (DID) is characterized by disruptions in identity, presenting as two or more distinct personality states often associated with early trauma. This case study examines a 20-year-old woman with DID, who experienced alternating
Stuti Sharma   +2 more
doaj   +1 more source

Electron-Impact Dissociation of Vibrationally-Excited Molecular Hydrogen into Neutral Fragments

open access: yesAtoms, 2019
We present convergent close-coupling (CCC) calculations of electron-impact dissociation of vibrationally-excited molecular hydrogen into neutral fragments.
Liam H. Scarlett   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

The Relationship Between Childhood Trauma and Shame: The Mediating Role of Dissociation

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
Previous research has found significant associations among childhood trauma, dissociation, and shame. Furthermore, the clinical literature suggests that dissociation may foster feelings of shame in individuals who were exposed to childhood trauma.
Gianluca Santoro   +3 more
doaj   +1 more source

Scapulothoracic dissociation

open access: yesThe British Journal of Radiology, 2019
Scapulothoracic dissociation is a rare and potentially limb- and life-threatening injury, that results from high-energy trauma. Scapulothoracic dissociation has the potential to be overlooked in the acute setting, especially in the setting of polytrauma. Therefore, a careful search for this condition should be performed in all patients with high-energy
Kimia Khalatbari, Kani, Felix S, Chew
openaire   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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